Anybody else dealing with pertussis?

[Kittery]

I'm just looking to commiserate. We officially have an outbreak.

[Elvish, BSN, DNP, RN, NP]

Please explain this further.

Otherwise, No. The non-seroconversion causes the infection, or the rate of that particular person's immune response causes this. NOTE: Pertussis IgM and IgA antibodies will usually only be present a short time after vaccination or infection. Otherwise, immune response happens when the message gets sent to the lymph. The difference in people's immune system function determines infection. People are infected and show no signs of infection, but can still shed. Macrophages, neutrophils, natural killer cells, dendritic, Tcells (in lymph), Bcells (lymph). OMG, the list goes on. Our immune systems are complicated.

Example: CD4+ T cells are a major T cell subset that plays a central role in immune system function when naive CD4+ T cells differentiate into effector and/or memory cells after encountering their cognate antigen via antigen-presenting cells (APCs). The phenotypes of effector CD4+ T cells differ depending on the stimulating conditions and can be categorized into various lineages. In the lungs, DCs bridge innate and adaptive immunity, and depending on context, they also induce various CD4+ T cell responses to infectious agents. During steady state, the lung contains two major subsets of CD11chi conventional ©DCs (CD103− CD11b+ cells in the lamina propria and CD103+CD11b− cells in the epithelial layer). (C&P that!)

I'm writing this because parents are told, "As long as your family members have all had their DPT shot, your baby will be fine. "Cocoon affect." BS, make them cover their cough. Ask them not to cough. Ask them to wash their hands. Pertussis is extremely contagious and will continue to be contagious even if every single person-all 7billion of us were vaccinated!

To all the people who are asked to re-vaccinate themselves because their titers are low, tell them your immune response still resides in your B memory cells located in your lymph. Because it does. My apology if this upsets people but this is all way more complicated than anyone realizes. And six injections is not the answer. Not at all. I will stop now.

I don't mean to pick on you, but I'm not sure asking someone with pertussis not to cough is realistic. It would be like trying to stop Niagara Falls; you can try, but it ain't gonna happen.

Coughing into one's elbow and good handwashing are good ideas no matter what we're dealing with, pertussis or otherwise.

[Spidey's mom, ADN, BSN, RN]

The baby may very well have gotten pertussis from Granny who didn't get her booster - Granny may never have gotten the pertussis vax to begin with.

This granny did! Before my granddaughter was born and so did my husband and our youngest son.

This frustrates me to no end.

Fortunately here in California, religious exemptions are no longer allowed.

People are crazy. . .

[Kooky Korky, BSN, RN]

Stupid anti-vaxxers. My son was reading a biography on Queen Elizabeth and they said her face broke out in white bumps. I said smallpox. Sadly, I couldn't tell him it was obliterated because of vaccines. I fear the worst is yet to come.

I am not thrilled about vaccinating, but I don't appreciate being called "stupid". It also probably violates TOS, so please don't name call. State your view nicely and be done with it, please.

As for Queen Elizabeth's white bumps - when was this?

I doubt any diseases have truly been obliterated. These little viruses and other microorganisms are intentionally kept alive, experimented with, used in warfare. They'll be here long after you and I are history.

Check out Plum Island, for example.

Also, what about herd immunity and the efficacy of vaccinations? Plus, you are assuming, I assume, that the current outbreaks we've had of measles, mumps, pertussis are due to someone not being vaccinated. That very well might not be so. The vax don't always work and/or the bugs might have mutated. Look at the history of malaria.

OK, peace.

[JessiJam]

There seems to be something about the acellular vaccine that doesn't confer as much immunity as whole cell pertussis vaccine (but that one caused many more vaccine reactions so I guess we don't win either way).

Critical point here.

In addition to the importance of maintaining full population participation, as well following through on full administration schedule for vax treatments, the efficacy of the vax itself attributes to its success.

There's a lot of data that needs to be gathered as to why there's been a drop in the success of Tdap itself, starting with the manufacturing process.

If the people in white lab coats can figure that one out, then they can hopefully work with the people in suits to get a revised vax policy underway.