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  1. This is a discussion on Math Again in Nursing Student Assistance, part of Nursing Student ... I'm doing some practice problems, and this is from nursesaregreat.com: A procainamide drip is...

    by Jan 22, '12
    I'm doing some practice problems, and this is from nursesaregreat.com:

    A procainamide drip is ordered (2 gm in 250 cc of D5W) to infuse at 4mg/kg/min. The patient weighs 165 lbs. Calculate the drip rate in cc/hr for which the infusion pump will be set at.

    165 lbs = 75 kg
    2gm = 200,000 mcg
    4mg = .004 mcg

    I'm trying to do the formula like this:

    solution cc
    __________ X 60min/hr X kg X mcg/kg/min = cc/hr
    drug mcg



    Am I doing this right? The answer should be 30, but that's not what I'm getting. I'm sort of hoping this problem has a mistake in it because it has fried my brain! I did, however, catch the preposition at the end of the sentence, so maybe I should have majored in English.
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    by RNrerun Jan 22, '12 12:00 pm
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  3. 11 Comments so far...

  4. Jan 22, '12 by
    I have tried it a few different ways and keep getting 2250/hr.

    250cc/2g x 4mg/kg/min x kg/2.2lbs x g/1000mg x 60min/hr= 2250cc/hr
    Last edit by Asmorris on Jan 22, '12 : Reason: error
  5. Jan 22, '12 by
    4mg = .004 mcg
    is wrong.

    4 MILIgrams (mg) = 4000 MICROgrams (mcg)

    And.. why are you working it down to mcg when the question is asking for mg/kg/min?

    Is it really suggesting you run it at 4mg/kg/min (which is a very HIGH dose) or did you have a typo there?

    When you break down numbers/values to smaller-than-required values, you introduce a greater risk of decimal place errors.
    Last edit by jmdRN on Jan 22, '12
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  6. Jan 22, '12 by
    2.25cc/hr if it was supposed to be 4 mcg instead of 4 mg
    Last edit by Asmorris on Jan 22, '12 : Reason: error
  7. Jan 22, '12 by
    I keep getting 2250 cc/hr.

    300 mg/min (amt needed)
    ______________________ X 250 cc = 3.75 cc/min X 60 = 2250 cc/hr

    2000 mg (amt you have)

    By the way, 2 grams = 2,000,000 mcg.
  8. Asst. Admin
    Jan 22, '12 by
    Procainamide is administered intravenously or orally. When administered intravenously, a loading dose should first be given, though care should be taken not to cause hypotension. Procainamide's major active metabolite is N-acetyl procainamide (NAPA), which is approximately equipotent with the parent drug as an antiarrhythmic agent. NAPA has an elimination half-life about twice that of procainamide, and it can reach somewhat higher plasma levels during chronic procainamide administration. Loading dose is 100 mg IV bolus given slowly over 5 minutes. Max dose is 17 mg/kg. Use is discontinued when dysrhythmia is suppressed, or if hypotension ensues, QRS complex widens by 50% or more, or maximum dose is achieved.

    Now the math.....you will find these very valuable
    DosageHelp.com - Helping Nursing Students Learn Dosage Calculations
    http://www.davesems.com/files/drug_d...lculations.pdf
  9. Jan 22, '12 by
    I like dosagehelp.com. Simplifies the questions. Like jmdRN says don't "over" convert your grams and milligrams. If you have a problem with both mg and gm, just convert one to the other. When you are taking a test, make sure that you remember which is a larger mass. If you have 1 gram of something, it's going to be 1,000,000 mcg. I think you found a problem with a typo.
  10. Jan 22, '12 by
    Well, in your problem, you say the dose is in mg/kg/min and then you're trying to work out the answer in mcg/kg/min. So there's problem #1. 4 mg/kg/min seems like an extremely high dose of procainamide... 300 mg/min? Seems unlikely.
  11. Jan 22, '12 by
    Wow. Thanks for all the help. I'm going to assume there's something wrong with this problem. I'm trying to re-learn all these calculations that I haven't done in years and years, and it doesn't take much to confuse me. I have been using dosagehelp.com to practice, and I'll check out the other one that Esmel reccommended. I'll have to take a medications test at the hospital, and I'm trying to get all this straight in my head before I go in there!

    Thanks!
  12. Jan 22, '12 by
    Good luck on the test!