Go back and reassess the efficacy of the med, at the time of expected onset or peak.
Monitor for sedation with narcotics or other sedative type drugs. Instruct pt. to call for assist before getting up, keep SR up, call bell in reach and document all of it.
Monitor or assess for common side effects, such as nausea or dizziness.
Monitor VS for cardiac drugs.
Monitor IV site for any IV med. The one I look for most on my student's drug cards is "how fast can you push, or how many minutes for piggy back".
Look in your drug book, most nursing drug books have a "nursing implications" paragraph for each drug.