prescribing Keflex with Allergy to PCN

  1. hi

    if a patient is allergic to penicillin, can a patient still be prescribed keflex? pharmacist tells me that patient cant take keflex due to allergy to pcn and a doctor who prescribed it tells me that unless a patient has a life threatening reaction to pcn, patient still can take keflex. so which one is it?

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    Joined: Jul '04; Posts: 966; Likes: 149


  3. by   JentheRN05
    I'm seriously allergic to PCN (anaphalactic shock type), yet I can still take Keflex. I don't know how this differs from one person to the next. I only can tell you my personal experience. I hope that helps.
  4. by   hollyster
    We had a surgeon who always ordered Keflex, even with PCN allergy.
    He said that the were molecularly dissimilar enough not to cause a reaction.
    Another surgeon put it better, why bother taking the chance when we have so many other meds.
  5. by   sirI
    I, too, prescribe Keflex to my PCN allergic patients. There is a cautionary issue and I weigh the benefits/risks beforehand....
  6. by   Nightcrawler
    I too have a PCN allergy and had never been prescribed Keflex until once about 5 years ago, when I was told that there would be no problem. After the second dose I began to experience a precursor to anaphylaxis where my lips and tongue became alarmingly swollen, and I began to have difficulty breathing.

    I ofcourse immediately discontinued the medication and required benadryl po for over a week before the swelling completely receded.

    This was during a period of time when I found that a lot of providers were questioning claims of allergy. During that 2 year period I don't know how many times that I heard " So how do you know that you are allergic to PCN?" It seems that I heard it every time I saw a MD.