IV Benadryl - pg.2 | allnurses

IV Benadryl - page 2

Anyone ever have weird side effects with IV Benadryl? I gave 25mg IV Benadryl to a patient diluted in 5 cc saline and almost immediately they started feeling 'a rush'. Then she went unresponsive and... Read More

  1. Visit  prnqday profile page
    0
    I had a pt. allergic to PO benny but not IV.
  2. Visit  noyesno profile page
    3
    One of my patients developed a "locked jaw" 10 minutes after I gave him IV benadryl. He wrote down, as he could not talk, that he needed more IV benadryl to fix the problem. I stated, "if I call the doctor to ask for more IV benadryl for an adverse reaction to IV benadryl he is most likely going to discontinue the medication completely, not order more of it." He begged for me to not call the doctor. I called the doctor, he discontinued the medication. The patient threatened to leave AMA and called the nursing supervisor.

    Moral of the story: If you want more of a medication, don't fake a reaction to it.
  3. Visit  Hanginten247 profile page
    1
    On two separate occasions, I have given IV Benadryl to middle-aged African American women and they had both had this coughing fit and severe confusion, then became obtunded for a minute or two. Scared the daylights out of me, but I specifically remember pushing over like 3 mins at least. Very interesting to hear about the acute anti cholinergic syndrome, might have happened.
    RunnerRN2015 likes this.
  4. Visit  crystal531 profile page
    0
    Quote from kmrn1737
    Anyone ever have weird side effects with IV Benadryl?
    I gave 25mg IV Benadryl to a patient diluted in 5 cc saline and almost immediately they started feeling 'a rush'. Then she went unresponsive and started seizing. I gave them Ativan and they stopped. She came around and didnt remember any of it.
    We were all baffled by what happened. Just wondering if anyone else ever had this happen.
    I have these symptoms myself with IV or IM benadryl. ..only when the hospital gives me there benadryl with preservatives in it. I can only have preservatives free, which I carry this rx around in my er protocol. I have Mastocytosis, which comes along with sensitivities to many medications. My symptoms are less with slow pushes of benadryl 50mg over 2 min except during a Mast cell disease attack which after eating foods high in histamines or salicylates, environmental toxins, lights, loud sounds, potent smells...try looking up tmsforacure.org and it will tell you more about this rare disorder.

    What helps me calm my dystonias are Ativan since valium is a DOA inhibitor.
  5. Visit  hherrn profile page
    1
    Quote from Sassy5d
    I'm one of those crazy slow ivp people. I always feel more comfy giving a med while a bag of ns is running. I always check, check, check if a med can go with ns and then give it in a port.
    Very important to anticipate the generalized possible effects of a med before you give it.

    I've had people ordered 4mg of Morphine and sometimes only end up getting 1-2 because they just can't tolerate it. Whether it drops their bp or they complain they really don't like the way it makes them feel or I see resp lower and spo2 drop.

    Most meds I give say ivp at least a minute, and it depends on the dosage but honestly, I mix that Benadryl in a small bag and hang it. 1 minute feels like a lifetime
    What can't go with ns?
    LJ85 likes this.


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