IV Benadryl - page 2

Anyone ever have weird side effects with IV Benadryl? I gave 25mg IV Benadryl to a patient diluted in 5 cc saline and almost immediately they started feeling 'a rush'. Then she went unresponsive and... Read More

  1. Visit  prnqday profile page
    I had a pt. allergic to PO benny but not IV.
  2. Visit  noyesno profile page
    One of my patients developed a "locked jaw" 10 minutes after I gave him IV benadryl. He wrote down, as he could not talk, that he needed more IV benadryl to fix the problem. I stated, "if I call the doctor to ask for more IV benadryl for an adverse reaction to IV benadryl he is most likely going to discontinue the medication completely, not order more of it." He begged for me to not call the doctor. I called the doctor, he discontinued the medication. The patient threatened to leave AMA and called the nursing supervisor.

    Moral of the story: If you want more of a medication, don't fake a reaction to it.
  3. Visit  Hanginten247 profile page
    On two separate occasions, I have given IV Benadryl to middle-aged African American women and they had both had this coughing fit and severe confusion, then became obtunded for a minute or two. Scared the daylights out of me, but I specifically remember pushing over like 3 mins at least. Very interesting to hear about the acute anti cholinergic syndrome, might have happened.

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