Vasoactive drugs

[WakingLife]

This is probably kind of a dumb question but I was just wondering what is considered a vasoactive drug? Is is pretty much the drugs that have the primary effects of working on cardiac function/ dilation/ constriction etc...or would you also consider drugs may have a cardiac or vascular secondary effect. (My immediate thought is Nitroglycerine, Levo, Nipride, Dopamine, Amiodarone, Cardiazem; not so sure about vasopressin, propofol, fenoldopam...) Thanks in advance for any responses!

[hrtprncss]

any meds that affects the blood vessels. fenoldompam and ddavp i would consider yes, ummm i donno about diprivan tho, i mean it's a benzo and can lead to hypotension but it's not it's primary effect.

[yoga crna]

any meds that affects the blood vessels. fenoldompam and ddavp i would consider yes, ummm i donno about diprivan tho, i mean it's a benzo and can lead to hypotension but it's not it's primary effect.

Diprivan a benzo?? Where did you get that information. I sincerely hope you are not administering Diprivan if you don't know its classification.

Yoga crna

[hrtprncss]

I mean I'm not a CRNA but I know that we use it as a sedative and it works on benzo receptors as well...doesn't it?

[Athlein1]

No.

[chadash]

Diprivan a benzo?? Where did you get that information. I sincerely hope you are not administering Diprivan if you don't know its classification.

Yoga crna

Could the confusion be because diprivan is used to sedate for cardioversion?

[Kiwi, BSN, RN]

Nitroglycerine, Levo, Nipride, Dopamine, Amiodarone, Cardiazem

Those are vasoactive drugs.

[ICUDOUCME?]

Diprivan a benzo?? Where did you get that information. I sincerely hope you are not administering Diprivan if you don't know its classification.

Yoga crna

I think this sounds a little harsh. Everyone can make a mistake. I run into this attitude a lot at work. The tone of your comment makes it sound like you are indignantly chastising this poster instead of trying to impart information.

People learn best in an environment where questions are not belittled or comments pounced upon.

[Pete495]

I can see the confusion, and I agree that Diprivan can be confused with the benzos by some persons.

By definition, diprivan is a general anesthetic, and also a sedative hypnotic used for anesthesia induction or long term use in ICU patients. Some anesthesia pracititioners use it during OR cases as well. Because of its anti-anxiety effects, I can see why it can be considered by some to be a benzo, but it is not a benzodiazepine. It's anti-anxiety effects are the result of the patient being asleep through general anesthestic properties.

On a side note, diprivan is such a great drug isn't it?

[gaspassah]

diprivan (trade)/propofol(generic) is a sedative hypnotic/general anesthetic depending on dose. it's mechanism of action is GABA mimetic. GABA is a neurotransmitter that when stimulated causes an inhibitory reaction neurologically. inhibitory meaning slows neuro function and or causes a sleeplike state depending on dose. some side effects of note, euphoria and or vivid dreams, antiemetic properties. painful on injection.

d

[maturner]

I mean I'm not a CRNA but I know that we use it as a sedative and it works on benzo receptors as well...doesn't it?

Propofol does not work on benzodiazepine receptors; however, benzo receptors effect GABA as does propofol. The differences in the drugs actions are a result of the different ways they interact within the GABA glycoprotein receptor complex.

[maturner]

diprivan (trade)/propofol(generic) is a sedative hypnotic/general anesthetic depending on dose. it's mechanism of action is GABA mimetic. GABA is a neurotransmitter that when stimulated causes an inhibitory reaction neurologically. inhibitory meaning slows neuro function and or causes a sleeplike state depending on dose. some side effects of note, euphoria and or vivid dreams, antiemetic properties. painful on injection.

d

David,

Good to see you are alive and well!

Mike