Published Jan 16, 2005
Headhurt, ADN
202 Posts
I was working the other night, and there was a pt who had a history of hemophilia needing an IV placed. The IV nurse was on the floor, and telling the resident on call that the patient had bled out the last time he had an IV placed. The resident told the IV nurse (who has been in the trenches for 20-plus years) that the patient had recently had a liver transplant, and was thereby cured of hemophelia. He explained that liver transplants cured all hematological disorders (i.e. sickle cell, hemophilia, etc). :uhoh21:
This must be really cutting edge research or something. We never learned about this in nursing school...
justcurious
18 Posts
Outcome of orthotopic liver transplantation in patients with haemophilia.
Gordon FH; Mistry PK; Sabin CA; Lee CA
Gut 1998 May;42(5):744-9.
BACKGROUND: Many patients with haemophilia have developed cirrhosis or hepatocellular carcinoma due to transfusion acquired chronic viral hepatitis. AIMS: To assess the long term outcome of all haemophilic patients reported to have undergone orthotopic liver transplantation. METHODS: Transplant centres of patients identified by medical database search were contacted and survival data assessed by Kaplan-Meier analysis. RESULTS: Twenty six haemophilic men (median age 46 years, range 5-63 years) underwent orthotopic liver transplantation in 16 centres between 1982 and 1996. Indications for transplantation were hepatitis C cirrhosis (69%), hepatitis B with or without C cirrhosis (15%), viral hepatitis related hepatocellular carcinoma (12%), and biliary atresia (4%). Six patients (23%) were infected with human immunodeficiency virus (HIV). Postoperatively, the median time to normal clotting factor levels was 24 hours (range 0-48 hours) and exogenous clotting factors were stopped at a median of 24 hours (range 0-480 hours). Four patients (15%) had bleeding complications. The one and three year survival of HIV positive recipients (67% and 23%) was significantly poorer (p = 0.0003) than that of HIV negative recipients (90% and 83%). Coagulopathy was cured in all patients surviving more than 12 days post-transplant. Six of the 20 patients (30%) with hepatitis C cirrhosis pretransplant had evidence of disease recurrence at a mean of nine months post-transplant. CONCLUSIONS: Hepatitis C cirrhosis is the most common indication for orthotopic liver transplantation in patients with haemophilia. Transplantation results in long term cure of haemophilia but may be complicated by the effects of HIV infection or recurrent viral hepatitis.
Wow...thanks for this. I shall print it off and take it to show everyone at work.
BittyBabyGrower, MSN, RN
1,823 Posts
I've heard a few in my time....did you know that Pregestimal CURES reflux...uh, could it be the Reglan and Zantac that you have the kids on?
RN4NICU, LPN, LVN
1,711 Posts
Pregestamil probably does have a hand in curing reflux. If the formula is so disgusting that the poor kids can't choke it down, it doesn't get the chance to come back up --- see how it works! :chuckle