Question

[amandajane]

What is the antidote for Dopamine?

[gaajr1, RN]

http://www.northshore.org/healthresources/encyclopedia/bioterrorism/hf045600.aspx

above is a link which gives all the info

[Whispera, MSN, RN]

that's a rather different question....what's your reason for asking?

[athena55, BSN, RN]

for dopamine or norepinephrine extravasation (the dermal necrosis and/or sloughing that occurs) it is phentolamine mesylate (Regitine).

You infiltrate the area with five to ten mg (diluted in ten to fifteen mil of NS). Inject in a "Star of David" design, if you will, around the affected area. It must be given within ten hours (if I remember correctly) of the extravasation.

Regitine is also used as a diagnostic aid for pheochromocytoma and given prior to a pheochromocytomectomy

If it is given IV it is used as an alpha blocker that will block the effects of catecholamines (on the alpha receptors)

athena

[Daytonite, BSN, RN]

The name of the drug is Regitine (phentolamine). It is an adrenergic blocker which dilates the peripheral blood vessels and (hopefully) prevents skin necrosis if the dopamine IV has infilrated and the drug has extravasated into the local tissues.