Question

http://www.northshore.org/healthresources/encyclopedia/bioterrorism/hf045600.aspx

above is a link which gives all the info

that's a rather different question....what's your reason for asking?

for dopamine or norepinephrine extravasation (the dermal necrosis and/or sloughing that occurs) it is phentolamine mesylate (Regitine).

You infiltrate the area with five to ten mg (diluted in ten to fifteen mil of NS). Inject in a "Star of David" design, if you will, around the affected area. It must be given within ten hours (if I remember correctly) of the extravasation.

Regitine is also used as a diagnostic aid for pheochromocytoma and given prior to a pheochromocytomectomy

If it is given IV it is used as an alpha blocker that will block the effects of catecholamines (on the alpha receptors)

athena