Jump to content
Nadine Buchanan

Nadine Buchanan LPN

Geriatrics, Home Care, Senior Care
Platinum Platinum Nurse
  • Joined:
  • Last Visited:
  • 9

    Content

  • 2

    Articles

  • 254

    Visitors

  • 0

    Followers

  • 0

    Points

Nadine Buchanan has 15 years experience as a LPN and specializes in Geriatrics, Home Care, Senior Care.

Nadine Buchanan's Latest Activity

  1. Nadine Buchanan

    The Problem with Aducanumab: Approved For Alzheimer's

    Thank you all for your thoughtful comments. I don't have any answers without doing more research for another article. I too will be watching for more answers. I merely wanted to bring up the controversy, and show both sides if I could. The reaction to those who left the FDA because they thought principals had been compromised is just rare.
  2. Nadine Buchanan

    Aging is Not a Disease: National Senior Citizens Day

    JBMom, MSN, NP, Thank you for your comments. I suppose you are right that there will always be those healthcare providers, but I can hope, right?
  3. Nadine Buchanan

    Aging is Not a Disease: National Senior Citizens Day

    Batsek2013,BSN, Thank you for your comments and support. And thank you for what you said about pregnancy and vital life stages. I agree wholeheartedly with you.
  4. Nadine Buchanan

    Aging is Not a Disease: National Senior Citizens Day

    AmoLucia, Thank you for your comments. "I will give that there some practitioners in desperate need of some politically correct intensive educational sensitivity retraining." -- that's who I meant to address. Thank you for that. Honeybee, Thank you for your comment. You sound like a very good CNA.
  5. Nadine Buchanan

    Aging is Not a Disease: National Senior Citizens Day

    Kitiger, Thank you for all of your good comments. I like your comment about development stages, and thank you for including pregnancy. Thank you for your support words about waiting until someone asks for help.
  6. Nadine Buchanan

    Aging is Not a Disease: National Senior Citizens Day

    Davey, Your points are all well taken. Kitiger is right, you make us think. I love a good lively conversation.
  7. Aging is not a disease. I feel very strongly about this, and I know many other nurses also do. Still, many nurses have a very different attitude toward seniors, and indeed, they reflect a lot of what society says about our elders. I want to remind myself and you to stop and reflect and examine our views and attitudes towards Senior Citizens and how we treat them. Aging is Not a Disease Many elders are bright, active, contributing members of their communities. Let’s emulate the Japanese and honor our seniors. There were 4,096,607 registered nurses (RNs) and 920,655 licensed practical nurses/licensed vocational nurses (LPN/LVNs) in the United States as of October 2019 (2020NurseandMidwife). I would venture to say most of us work with seniors at least part of the time, whether we are working in a doctor’s office, hospital, or of course, if we are working in Skilled Nursing or managed care facilities. So, the numbers tell us we affect many older people. I have watched too many nurses talk baby talk to these beautiful people in our charge. Those nurses are well-intentioned, however misguided. There is also a prevalent attitude that these people are naturally disabled. First of all, it is not always true. I knew one man, who would be considered elderly, who went on a mountain climbing trek for a vacation. I know another senior, 80 years old this month, who rides approximately 20 miles a day on his bicycle for exercise. You can probably think of those in your own life who are still very active and taking care of themselves, and perhaps even taking care of others. For those that have become weakened or even handicapped with age, we need to step back, let them do everything they can for themselves (I know, this takes a lot of patience), and then offer to assist before jumping in to do anything for them. History of this Day It was President Ronald Reagan who declared August 21 as National Senior Citizens Day. He did this when he signed Proclamation 5847. At that time, he said: “Throughout our history, older people have achieved much for our families, our communities, and our country. That remains true today, and gives us ample reason this year to reserve a special day in honor of the senior citizens who mean so much to our land,” Reagan proclaimed. “For all they have achieved throughout life and for all they continue to accomplish, we owe older citizens our thanks and a heartfelt salute. We can best demonstrate our gratitude and esteem by making sure that our communities are good places in which to mature and grow older — places in which older people can participate to the fullest and can find the encouragement, acceptance, assistance, and services they need to continue to lead lives of independence and dignity.” (National Senior Citizens Day – August 21, 2021) Of course, it is poignant that Ronald Reagan himself ended up battling one of the Alzheimer’s diseases; one of the most debilitating diseases we face. How We Treat Them is How They’ll Behave The United States’ attitude toward Senior Citizens gets pretty low marks. Watch the advertising, and the TV shows, and the movies. So much of the time elderly are depicted as foolish, slow, or ludicrous. We all know people who play into that. I have even known co-workers at Skilled Nursing facilities who made very bad, deprecating jokes about older people in general. We can do better. All of us, seniors included, tend to act the way we’re treated. It’s a natural reaction. Remember the old adage “treat someone like a horse long enough, eventually they’ll put on a saddle”. I may be misquoting a little there. Anyway, for our own good and the good of others, let’s try to have a more healthy, positive perspective about aging in this country. We need to realize what our elders can give us – wisdom, kindness, encouragement, the benefits of their vast experiences. Many seniors contribute to the betterment of our communities with their volunteer work. Let’s honor all of them on this National Senior Citizen’s Day.
  8. Nurses who work with Alzheimer patients and their families do not have to be told about the anguish these families go through as they watch a loved one leave them as they are still physically present. And in the early stages of the disease, the patient also watches what is happening. They have needed hope for a long time. So now there is a new drug, Aducanumab. There is a catch, however, a controversy. I will attempt to present both sides of this controversy, giving voice to those who support the drug and those who don’t. The approval and use of Aducanumab feels like a storm; it has happened so fast. It was approved just this June by the Food and Drug Administration. To those of us paying attention, it feels like it has already been a few years. Three members of the Food and Drug Advisory committee that reviewed the findings of the tests for Aducanumab resigned over its approval. Yet the Food and Drug Administration backs its decision, and patient advocacy groups are thrilled at this seeming breakthrough. Many families and loved ones of patients, and patients themselves, see it as making headway. It is the first novel therapy to be approved for Alzheimer’s since 2003. Aducanumab is an enormous aberration for the FDA. Throughout history, medicine men and later legitimate pharmaceutical companies could sell their wares without proving that they actually work. That ended with the debacle of thalidomide in the 1950s and 1960s. Around the world, many women gave birth to babies with severe birth defects because of this drug that was given for nausea. Dr. Frances Kelsey worked at the American Food and Drug Administration at the time. He pretty much single-handedly made sure the drug did not enter the U.S. Marketplace. Soon after that, the U.S. Congress passed a law (1962) that required pharmaceutical companies to prove extensive drug testing before any medicine can be put to market. Aducanumab (to be marketed as Aduhelm) has been approved against the recommendation of the FDA’s own committee. It has been reported several places, perhaps first, and most notably, by Laurie McGinley in the Washington Post, that the Peripheral and Central Nervous System Drugs Advisory Committee was asked to vote on the drug’s effectiveness. There were a few questions about the evidence. There was not one “yes” vote. Ten members voted no and one uncertain. Yet Aduhelm was still approved under the umbrella of what is known as an accelerated approval pathway. It was approved and announced on June 7, 2021.1 The Food and Drug Administration’s Center for Drug Evaluation and Research director is Patricia Cavazzoni, M.D. She was quoted by the publication Salud America! as saying on June 7, “Alzheimer’s disease is a devastating illness that can have a profound impact on the lives of people diagnosed with the disease as well as their loved ones. Currently available therapies only treat symptoms of the disease; this treatment option is the first therapy to target and affect the underlying disease process of Alzheimer’s. As we have learned from the fight against cancer, the accelerated approval pathway can bring therapies to patients faster while spurring more research and innovation.”2 At least one other doctor echoes her position. Dr. Rany Aburashed is Chief of Neurology at Memorial Healthcare in Michigan. Memorial Healthcare is a hospital with an institute for neuroscience. Jacqueline Howard reported that he was quoted from an email: “…. What is really exciting is that Aducanumab is the first new FDA-approved Alzheimer’s treatment in 20 years, and we’re optimistic this will spark a wave of new research and innovation in this space. Patients are excited for that, too, and if aducanumab is the first step toward that bright future, patients are eager to be part of it.”3 Biogen and its Japanese partner Eisai are the pharmaceutical companies that developed Aducanumab. They claim that the drug slows the decline of mental acuity and cognitive health in Alzheimer’s patients. Again, Jacqueline Howard of CNN reports that Biogen’s documents presented to the committee at the FDA stated that the patients that were given high-dose aducanumab showed 22% less clinical decline in their cognitive health than those who were given a placebo. This was after 18 months of medication. Aducanumab, or Aduhelm, targets amyloid beta plaques. Jacqueline Howard of CNN quotes Dr. Aburashed as writing: “This is the first antibody directed treatment for Alzheimer’s disease that targets the main possible cause of the disease, which many feel is related to the deposition and accumulation of a protein called amyloid beta. The antibody binds to aggregates of the amyloid protein and appears to preferentially target the amyloid plaques in the brain as opposed to those in the blood vessels.”4 Still, the tests were not enough to satisfy the committee at the FDA. And their reaction to Aduhelm’s approval is radical. The first to resign from the FDA for this was Dr. Joel Perlmutter. He is a neurologist at Washington University School of Medicine in St. Louis. He was quoted as saying, “Approval of a drug that is not effective has serious potential to impair future research into the treatments that may be effective.” He was followed in his exit by Dr. Aaron S. Kesselheim, professor of medicine at Harvard Medical School. Dr. David Knopman was the third to leave the FDA. He is a clinical neurologist at The Mayo Clinic. According to several publications, including The Washington Post, he wrote in an email to FDA officials “Biomarker justification for approval in the absence of consistent clinical benefit after 18 months of treatment is indefensible.”5 The problem with Aducanumab, or Aduhelm as it will commonly be known, is that patients and families are so desperate for something, anything that just might work. There are two major issues with the drug. It has been known to cause the brain to swell and hemorrhage. The other drawback is that it costs $4,312 per infusion, making an annual cost of $56,000 for a high dose. It is infused intravenously over about an hour every four weeks. Nurses know the implication of that – it acts fast, and there is little time to turn back if there is an adverse reaction. Is there an antidote yet to Aduhelm? Nevertheless, people are anxious to take the drug or see their loved ones take the drug. Kurt Rehwinkel is a spouse to a patient taking Aduhelm. He does not understand people who want Aduhelm kept off of the market. He said in an interview with NPR’s Jon Hamilton, “I wondered, do these people really have loved ones who have a stake in the game? Are they losing a little bit more of their loved one every day to the disease?”6 As nurses, one of our jobs in all of this will be, as always, to listen empathetically to these patients and their families, giving them as much time, space and reprieve as we can. As always, we have to leave our own opinions to the side while offering compassionate care. References/Resources 1,5 Two Members of an FDA Advisory Committee Quit After Approval of Controversial Alzheimer’s Drug 2 FDA’s Decision to Approve New Treatment for Alzheimer’s Disease 3,4 New Alzheimer’s Drug Aducanumab: Cost, Side Effects, Timeline and Other Questions Answered 6 For Those Facing Alzheimer’s, a Controversial Drug Offers Hope FDA Grants Accelerated Approval for Alzheimer’s Drug Aducanumab (Marketed as Aduhelm) Information FDA’s Decision to Approve New Treatment for Alzheimer’s Disease Three FDA Advisers Resign Over Agency’s approval of Alzheimer’s Drug FDA Approves New Drug for Alzheimer’s, But Scientists Divided Over Decision FDA Grants Accelerated Approval for Alzheimer’s Drug