It can be administered in any setting, technically. But it's unlikely to be administered in the home unless the family is super hands on, no pun intended. Definitely regularly used in the ER, not sure on a general floor of a hospital, but definitely on the psych floor or crisis unit. Not sure if via IV in the ICU since I have never worked ICU. I know there is something called "ICU psychosis" but am not sure what they use to treat that condition.