EricJRN, MSN, RN 1 Article; 6,681 Posts Has 17 years experience. Dec 18, 2007 I moved your post to its own thread. Good luck to you.
UM Review RN, ASN, RN 7 Articles; 5,163 Posts Specializes in Utilization Management. Dec 19, 2007 This link might be a little complex, but I found it very helpful:http://www.sepsis.com/media/microcirculation_video.htmlThis link has a lot of information:http://www.kidneyatlas.org/book2/adk2_07.pdf
Daytonite, BSN, RN 4 Articles; 14,603 Posts Specializes in med/surg, telemetry, IV therapy, mgmt. Has 40 years experience. Dec 19, 2007 hi, bnzhd, and welcome to allnurses! :welcome:the basic pathophysiology is that once bacteria enter the bladder, local defense mechanisms in the bladder break down and the bacteria invade the bladder mucosa and begin to multiply. the bacteria that have lodged in the mucosa cannot be eliminated by urination. inflammation also occurs; it is the general response to any bacterial invasion which results in vascular permeability. because of the vascular permeability, bacteria that have invaded the bladder mucosa are able to escape into the blood stream and this is the actual start of septicemia. once the bacteria enters the blood stream they release endotoxins and the symptoms of bacteremia are produced.also see. . .the pathophysiology of the inflammation response on this thread: https://allnurses.com/forums/f50/histamine-effect-244836.html
UM Review RN, ASN, RN 7 Articles; 5,163 Posts Specializes in Utilization Management. Dec 19, 2007 Hi, bnzhd, and welcome to allnurses! :welcome:The basic pathophysiology is that once bacteria enter the bladder, local defense mechanisms in the bladder break down and the bacteria invade the bladder mucosa and begin to multiply. The bacteria that have lodged in the mucosa cannot be eliminated by urination. Inflammation also occurs; it is the general response to any bacterial invasion which results in vascular permeability. Because of the vascular permeability, bacteria that have invaded the bladder mucosa are able to escape into the blood stream and this is the actual start of septicemia. Once the bacteria enters the blood stream they release endotoxins and the symptoms of bacteremia are produced.You said it so much better than I could've. Thanks!
Daytonite, BSN, RN 4 Articles; 14,603 Posts Specializes in med/surg, telemetry, IV therapy, mgmt. Has 40 years experience. Dec 20, 2007 You said it so much better than I could've. Thanks!Ha! Ha! I actually used three different resources. Some of it I had to pull out of two different sections of Pathophysiology: The Biologic Basis for Disease in Adults and Children, third edition, by Kathryn L. McCance and Sue E. Heuther and then turn it into "easy reading".
