Cephalosporins?

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Specializes in M/S Short Stay/TCU.

Pharm2 Class...

As we go up the generations of cephalosporins from 1st - 4th gen. is their increasing resistence to destruction by the beta - lactameses? Which means that the beta - lactamese enzymes are not effective against cephalosporins? Please clarify for me? Thank you:D

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Specializes in Critical Care.

There is indeed an increase in resilience to β-lactamases as you go from first to fourth generation.

However, as there are many different types and strains of β-lactamases, susceptibility testing on cultures is necessary to definitively establish whether or not the antibiotic is suitable.

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Specializes in med/surg, telemetry, IV therapy, mgmt.
As we go up the generations of cephalosporins from 1st - 4th gen. is their increasing resistence to destruction by the beta - lactameses?

What is your question? It doesn't make grammatical sense.

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