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Discussion

Lab question- please help!

Hello,

I have a lab question I am wondering if someone could help me with...2.5 year old sick on and off for a year with URI's, high fevers, rashes, N&V, lethargy, pallor, night sweats...Her most recent labs indicated low lymphocytes, low abs lymphs, high ESR, high granuloyctes, and high immunoglobulin IgM. (Also, her lymphocytes have been dropping for 1 year and granulocytes rising for 1 year.)

I am confused as to the cause...I know both granulocytes and lymphs fight off infection, but what is the significance when all put together? Also, I thought if there was an active infection that the lymphocytes would be high and not low?

Thank you so much for any assistance you can provide!!!

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    What could cause low WBC/lymphs when you would expect them to be elevated?

    Where do granulocytes come in the hierarchy of blood cell production?

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    Need numbers. Also, do URIs typically last for a YEAR? What role could an immune system that doesn't seem to be functioning appropriately play in that?

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    That kid needs a hematology/oncology consult ASAP.

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