In renal disease, what is GPA?

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Specializes in Private Duty Pediatrics.

What does GPA stand for?

How do MPO antibodies relate to GPA?

I tried WebMD, but couldn't find how MPO antibodies relates to kidney disease. Is it a general marker for organ damage?

The only "GPA" I could find was grade point average. That doesn't help.

A family member has this diagnosis, and is being treated as we speak. But extended family members are asking me questions, and I don't even know how to look it up. I need to know what GPA stands for.

Thanks.

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What does GPA stand for?

How do MPO antibodies relate to GPA?

I tried WebMD, but couldn't find how MPO antibodies relates to kidney disease. Is it a general marker for organ damage?

The only "GPA" I could find was grade point average. That doesn't help.

A family member has this diagnosis, and is being treated as we speak. But extended family members are asking me questions, and I don't even know how to look it up. I need to know what GPA stands for.

Thanks.

Is it "glomerular polyanion"? That's my best google-dependent guess.

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Specializes in Private Duty Pediatrics.
Is it "glomerular polyanion"? That's my best google-dependent guess.

She has albuminuria and polyuria, so that fits. Thanks.

I'll talk to her mother before disseminating any information, but I wanted to at least do my homework first. Thanks.

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Specializes in Private Duty Pediatrics.

Auto-immune problems run in that family, so this could be it, too.

Her mom said the MPO antibodies were "off the chart", and a major factor in diagnosing GPA.

I'll read up on both of these. Thanks.

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Specializes in Nephrology, Cardiology, ER, ICU.

Here you go:

ANCA associated diseases: (usually presented as rapidly progressiveglomerulonephritis)C-ANCA: associated with Wegener's granulomatosis. When test is positive, confirmedby demonstrating positive anti-protease 3 antibody (anti-PR3). Remission associatedwith loss of C-ANCA. Active disease associated with elevated ESR and disease activitycan be estimated by changes in ESR.P-ANCA: associated with microscopic polyangiitis. Also seen with crescenticglomerulonephritis (without evidence of systemic vasculitis). When test is positive,confirmed by demonstrating anti-myeloperoxidase antibody(anti-MPO). The remission isassociated with loss of P-ANCA

https://www.uthsc.edu/nephrology/documents/serologic-testing.pdf

We ask that per our terms of service, we can not answer medical questions....this is just general info and we strongly urge you to have your family member discuss their diagnosis and care with their nephrologist.

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