Hyperglycemia Question

oops wrong thread!

What causes diabetics that are hyperglycemia to feel nauseous and vomit? What's going on in the body to make this occur?

Motility decreases are seen with hyperglycemia. The associated sensation of abdominal distension via mechanorecptors may play a role. Here's an abstract that has good info:

Geoffrey S. Hebbard, Melvin Samsom, Jane M. Andrews, David Carman, Ben Tansell, Wei Ming Sun, John Dent and Michael Horowitz

Abstract Hyperglycemia slows gastric emptying andincreases the intensity of perception of gastricdistension during fasting and small intestinal nutrientstimulation. In order to examine the possibility thatabnormalities of gastric electrical rhythm may be associatedwith the effects of hyperglycemia, the gastricelectrical rhythm (cutaneous electrogastrogram) and theperception rating scores for upper gastrointestinal sensations (visual analog scale) were examined.Studies were performed during intraduodenal triglycerideinfusion in 10 healthy volunteers under euglycemic andhyperglycemic (15 mmol/liter) conditions. During fasting, hyperglycemia had no effect oneither gastric electrical rhythm or sensation.Intraduodenal triglyceride infusion was associated withan increase in bradygastria (3.6 cpm) wasmore prevalent during hyperglycemia when compared toeuglycemia (25 ± 10% vs 1 ± 1%, P

basically, vagal response.