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max.. keep in mind that antacids change the ph which influences the absorption of other meds. it can increase their effect or decrease. this is why is recommended to give it 1 hr between certain meds such as cimetidine and rantidine.
also a huge one is that all antacids cause enteric coated meds to dissolve in the stomach. so same here: administer them 1 hr apart from the enteric coated meds and weakly acidic drugs (digoxin, phenytoin, tetracycline). because if you don't then the enteric coated med will dissolve in the stomach. the whole reason why it is coated is to bypass the stomach. if these meds are for say dissolved (opened) in the stomach it can cause ulcerations. they are to dissolve in the intestine. i hope this helps a little.
maxandruby
39 Posts
Could anyone tell me why drugs under antacids class need to be given 1 hr ac or 2 hr pc other meds?
Lots of thanks in advance.
Max