Expel air from pre-filled NESP injection?

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Do I need to expel the air from the pre-filled plastic syringe (NESP) after connecting the needle (as I see the bubble is quite big)? 

Thanks a lot.

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Specializes in Specializes in L/D, newborn, GYN, LTC, Dialysis.

What do the instructions say?  I have never given this one. We give Mircera where I work.

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I can't imagine a reason that you would not want to remove the air prior to administering the medication. Realistically if you are administering IV through the HD machine any air is just going to get caught in the chamber, however a large enough bubble could cause an air detector alarm and the ensuing PIA to clear the air. If it is going SQ than it stands to reason that you would not want to add air to the administration.  

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