Magsulfate, BSN, RN 1,201 Posts Specializes in ICU. Has 13 years experience. Jan 8, 2009 . I would be much more comfortable giving big ole honking ativan boluses on a vent patient than I would pushing diprivan.Do you realize that diprivan has a very short half life, you can watch a patient, turn off the drug and in a matter of 5 minutes the diprivan has wore off. But on the other hand, Ativan lasts for HOURS and in my opinion is a much more dangerous drug than Diprivan when used to sedate someone. You can't bring a patients BP up by just "turning off" the Ativan, like you can with Diprivan.