Cushing syndrome

RaggedyRN · Jul 15, 2005

hi guys!
im studying for my nclex-rn test and i found the issue of cushing syndrome and addison disease very confusing.
is hyperkalemia occurs in addison disease? yes
because i remember that high blood pressure and elevated sodium levels-is about cushing syndrome.
welp, its confusing. could you help me out with that please?
thanks a lot

cushings patho:

increased cortisol -> increased gluconeogenisis -> hyperglycemia

increased aldosterone -> sodium and water retention, potassium loss

addison's patho:

decreased cortisol -> decreased gluconeogenesis -> hypoglycemia

decreased aldosterone -> sodium and water loss, potassium retention

this is from my school notes...hope it helps :)

chickey

Woman_in_love · Jul 15, 2005

Cushings Patho:
Increased cortisol -> Increased gluconeogenisis -> hyperglycemia
Increased aldosterone -> sodium and water retention, potassium loss
Addison's patho:
decreased cortisol -> decreased gluconeogenesis -> hypoglycemia
decreased aldosterone -> sodium and water loss, potassium retention
This is from my school notes...hope it helps :)
Chickey

It sure does!

Thank you so much, i guess the answer in my book was wrong which confused me. It said that in Cushing syndrome patient will have a hyperkalemia. Bums!:)

suzanne4, RN · Jul 15, 2005

Which book were you using?

Woman_in_love · Jul 15, 2005

Which book were you using?

Its CD from the book Saunder's "Comprehensive review for the NCLEX-RN" examination" by L.A.Silvestri.

I like this book but i guess as a human beings they do mistakes sometimes.

There was a question like this

What would you expect in client with Cushing syndrome.

1)Glucose 110 mg/dl

2) White cells-6000

3)Platelets-200000

4)Potassium-5.5

I answered the glucose thing and CD answer was potassium-5.5

suzanne4, RN · Jul 15, 2005

I would have gone with the potassium also. In Cushings, and because of the steroid use, the glucose level is going to be much higher.....usually in the 250 to 300 range during an acute episode.

What exactly did the book say?

thursdaygrl · Jul 15, 2005

I keep Cushing's and Addison's straight this way:

I just remember that they are both diseases caused by hypo- or hypersecretion of the Adrenal gland. If you remember that the adrenal gland secretes corticocorticoids (I always think "sugar") and mineralcorticoids (I think "salt"), you can pretty much figure out the two diseases of Cushing's and Addison's.

Just remember: Cushing's=HYPERsecretion=hyperglycemia (increased sugar), hypernatremia (increased salt) so therefore--hypokalemia, hypocalcemia

Addison's=HYPOsecretion=hypoglycemia (low sugar), hyponatremia (low salt), so therefore = hyperkalemia, hypercalcemia

Once you remember these ups and downs of the two diseases, you can pretty much figure out the disease symptoms. You also have to remember that the adrenal gland also produces androgens (sex hormones) which leads to hirsutism (male and female) and male pattern baldness (females) in Cushing's.

I take the test tomorrow morning at 9 and those are basically the only two diseases I feel good about! :) Now ask me a question about meds and I'm toast.

Good luck on the test!

Woman_in_love · Jul 15, 2005

Then why hyperkalemia is the right answer?

suzy253, RN · Jul 15, 2005

oh yeah....endocrinology...my favorite (NOT). :rolleyes: I still get confused. I'm going to copy some of these into my notes.

Woman_in_love · Jul 17, 2005

Hi everyone!

I wanted to know who's responsibility it's gonna be when RN delegates care to a nursing assistant or LPN and the mistake in care happens.

I remember that there is some type of delegation when RN is responsible and some type when the LPN/CNA will be held responsible.

Can anyone explain this to me please?

I guess those things do show up in NCLEX-RN, so i better know them:)

Thanks

junglern · Jul 19, 2005

Cushings Patho:
Increased cortisol -> Increased gluconeogenisis -> hyperglycemia
Increased aldosterone -> sodium and water retention, potassium loss
Addison's patho:
decreased cortisol -> decreased gluconeogenesis -> hypoglycemia
decreased aldosterone -> sodium and water loss, potassium retention
This is from my school notes...hope it helps :)
Chickey

Like a miracle by the first time, i really understand those pathos, thank you so much!

I am taking my exam on the 29 8 am in Ny, i am driving myself crazy and with hight anxiety levels, looking in how many things that i don't feel totally ok .

Any tips!

Thanks again.

Ulices.

dinogwapo · Jul 3, 2009

Its CD from the book Saunder's "Comprehensive review for the NCLEX-RN" examination" by L.A.Silvestri.
I like this book but i guess as a human beings they do mistakes sometimes.
There was a question like this
What would you expect in client with Cushing syndrome.
1)Glucose 110 mg/dl
2) White cells-6000
3)Platelets-200000
4)Potassium-5.5
I answered the glucose thing and CD answer was potassium-5.5

we have the same problem

what I know in Cushing and Addison's is the 3 S (Salt, Sugar, Sex)

in Cushing everything is increased: HyperNatremia, Hyperglycemia, Increase in Sex Hormones therefore potassium and calcium becomes low. That is why You decrease Salt in the diet and you increase your potassium.

in Addison's everything is low so: Hyponatremia, Hyperglycemia and decrease in Sex Hormones.. so potassium and calcium becomes high.

im pretty sure the question is wrong