Nurses can change the tide when they have a thorough understanding of the factors driving the misinformation as well as the motivations of those spreading the misinformation. This knowledge equips the nurses to respond to patients and members of the community who present with inaccurate information, confusion, and mistrust towards public health intervention recommendations including social distancing, masking and most importantly, vaccination. This understanding will empower nurses to stay empathetic but effective in mitigating the effects of misinformation or disinformation