So, I wanted to challenge myself this year and decided that I would submit a proposal for a presentation for the American Association of Nurse Practitioners 2019 Conference in Indianapolis. Here is some info that I shared and hope that it might be useful for others:CKD or chronic kidney disease is becoming more prevalent in the US. In fact half of the US population between 30 and 64 years of age will develop some degree of CKD during their lifetime. The most common reasons for advanced CKD and in turn, end stage renal disease (ESRD) is hypertension and diabetes. It is vitally important that these two chronic diseases be controlled at all costs in order to prevent renal dysfunction. I attended a session earlier where the presenter stated that the number of patients advancing to ESRD had decreased. However, what he didn't mention was that more patients are dying BEFORE they reach ESRD. It's recommended referring your chronic kidney disease (CKD) patient to a nephrologist when their estimated glomerular filtration rate (eGFR) reaches 30 or CKD stage 3. (Stage 5 CKD is end-stage renal disease). Though the patient might still remain stable for years to come, by establishing with a nephrologist if there is quick deterioration or other issues, they can easily be addressed. So the example I used is that you sent your CKD stage 3 patient to nephrology and they progressed to ESRD and started on hemodialysis. So, are you as the PCP done with the patient? They will still need preventive health maintenance screenings, annual exams, immunizations (just as an aside, if the pt is on chronic hemodialysis, immunizations specifically flu and pneumonia will probably be given at the dialysis unit). And unfortunately, your patient can have other non-renal related illnesses or injuries. Plus, and perhaps even more important, the PCP has a long-standing relationship with the patient so a continued relationship is important. It's very important all meds are renally dosed. Many of us use Epocrates which is a decent reference. However, when you look at some meds and under renal dosing they say “undefined” you might need to look further. I will use either UpToDate or I go directly to the drug manufacturer or consult with a pharmacist. I also advise patients with CKD/ESRD to notify their nephrology office/provider of any new meds. This is vitally important so that if there is an issue, it can be resolved prior to taking any new meds. It is also important to remember timing of meds if the patient is on dialysis. Is it a medication that will readily dialyze out? For this, you can use an app called Dialysis of Drugs. Its put out by the Renal Pharmacy Consultants and it gets updated every year. There is a cost for the app and its available on the App Store and Google Play. Avoid nephrotoxins especially NSAIDs. However, anuric dialysis patients can have NSAIDs provided they have no active bleeding or history of GIB from NSAIDs. Of course, they must be renally dosed. When a patient progresses to CKD stage 4, the nephrologist will probably be discussing dialysis with the patient. There will usually be a discussion about modalities and arrangements will be made to place an access. If the patient is to receive hemodialysis, a fistula or graft is placed in one arm after vein mapping occurs to determine the potentially most successful vessels. Obviously, don’t take BPs in the arm where there is dialysis access. However, it's important that you not take BPs or do lab draws or glucose sticks in a limb where dialysis access is planned. Hopefully, the pt will make you aware of this. Many practices utilize special bracelets for patients to wear to indicate to other healthcare providers that they either have a dialysis access or one is planned. Of course, avoid contrast if at all possible. If contrast is needed, dose reduction is always ordered so that the smallest amount of contrast is utilized. If you need to order an MRI for a dialysis patient it is vitally important that you notify the dialysis unit if gadolinium is used. Gadolinium can cause nephrogenic systemic fibrosis (NSF) which though rare is very serious. It is similar to scleroderma and causes swelling and tightening of the skin at the joints. The issue is that this doesn’t happen immediately but rather months to years later. If a dialysis patient receives gadolinium it is necessary to dialyze the pt three days in a row as gadolinium does not readily dialyze out.Last but not least, always use a solid drug reference. Hope you found some of this useful. 10 Down Vote Up Vote × About traumaRUs, MSN, APRN Trauma Columnist 88 Articles 21,268 Posts Share this post Share on other sites