anti-coagulant question

[NurseNature]

Why is vitamin K contraindicated with Warfarin, but not with other anti-coagulants like dipyridamole and aspirin?

Also, I read somewhere that dipyridamole and aspirin together (agrenox) was to be used with caution with asthmatics and such. I cannot come up with any reasons for this. My Davis drug book doesn't always expand as much as I would like it to sometimes. It is awesome, but I would like even more detail if there are better books available.

[leslie :-D]

A-Fib is the result of ectopy in the conduction system of the heart. A-Fib does not result from clot formation, but vice versa. Clots do not form in one of the left chambers, they form in one of the upper chambers, or atria.

this is what i was referring to, re left chambers:

"Second, because the heart is no longer pumping blood into the ventricles, the blood in the atria (particularly in a small part of the left atrium-the left atrial appendage) becomes relatively stagnant. There is a small risk that, over time, the stagnant blood will form a blood clot. If a blood clot forms, it may eventually enter the left ventricle and be pumped out into the body".

http://www.cardiologychannel.com/afib/index.shtml

and yes, i was referring to coumadin as the prophylactic tx in preventing stroke.

leslie

[Virgo_RN, BSN, RN]

Ah, I see. I thought you meant left chambers as in the left atrium and left ventricle.