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I really don't think you should have any problems landing a job if you are seeking one in an LTAC - there seems to always be a market for experienced nurses. Switching to acute care might be more problematic.
I would strongly advise you to make sure that you try to coordinate your efforts so that you wait to decide on a housing location until you have a job lined up -- otherwise, you could be locked into a soul-deadening commute. It's hard to offer any other advice since you did not indicate any other particulars.. where you are moving from, family situation, etc.