SSRI v MAOI

  1. 0
    Can someone please explain the difference between SSRIs and MAOIs? How do these drugs function in the body?
  2. 3 Comments so far...

  3. 1
    Not going to do all of the research for you...but here's something to get you started

    SSRI: selective serotonin reuptake inhibitors.
    Translation: helps prevent serotonin from being reuptook (?), resulting in higher serotonin levels
    Includes fluoxetine (Prozac), setraline (Zoloft), citalopram (Celexa) and a few other common antidepressants.

    MAOI: monoamine oxidase inhibitors.
    Translation: inhibits monoamine oxidase.
    Some older antidepressants were of this type. Noted for having severe side effects, severe and even fatal interactions with many other psych AND non-psych medications, and for requiring dietary restrictions (notably, a low-tyramine diet). So it's often prescribed as a last-resort when all else fails.
    Esme12 likes this.
  4. 0
    We are happy to help but like merriwhen says...we wont do it for you. What do you have so far? What is your understanding of these drugs?
  5. 0
    Think about your physiology. What does monoamine oxidase do?

    If you understand that you will understand not only the difference between the two but also why MAOIs have a large ADR profile.


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