I don't personally wear them, but my father-in-law does due to his diabetes and it's effect on his legs and feet. He wears compression hose was well and puts the support socks over those to cushion his heels and the bottom of his feet.
If you want to learn a little more about support socks you can read some information that I have gathered on diabeticssupportsocks.com
. While my site is specifically about how support socks aid diabetics, I also offer information and advice about support socks in general for athletes and anyone who is on their feet for long periods of time.