How to reconstitute amoxicillin?

Nurses Medications

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I'm trying to figure out how much water to add to amoxicillin suspension. Unfortunately there is no information on the bottle or on the insert that tells you how to reconstitute it. It's supposed to make 120ml, 250mg per 5ml. I can't find any info anywhere about how much to add to make 120ml. If anyone knows or know where I can find out I'd really appreciate if you could tell me.

Thank you

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Specializes in pediatrics, public health.

Is there a pharmacy where you work that you can call and ask? If not, can you ask any of the other nurses where you work? I think they would be a better source of information than an Internet board.

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Check the pdr or other Drug manual.

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Are you sure you checked the bottle well? Ours comes with directions right on it, but the print is quite small and easy to miss.

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Specializes in Acute Care, Rehab, Palliative.

Does your floor not have a IV med handbook. Our floor has one that gives all info on preparing and administering. Our amoxicillin comes with directions on the bottle too.

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Specializes in PACU, OR.

Bottle Size Amount of Water Required for Reconstitution

100 mL 74 mL

150 mL 111 mL

Each teaspoonful (5 mL) will contain 250 mg amoxicillin.

I checked that link-I see it only mentions 200 and 400mg doses. The above is the correct reconstitution, but the OP mentions a 120ml bottle. Op, I would recommend that you first check what the quantity is supposed to be after reconstitution; if you are correct and it is supposed to be 120ml, the amount of water, judging by the above table, would be in the region of 89ml.

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Hi, hope you dont mind, working on this for practice and got 90 mL !!

I did the ratio proportion, however I used the 200mg table. My question is, is there a formula for the 250mg?

Thanks :)

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Specializes in PACU, OR.
Hi, hope you dont mind, working on this for practice and got 90 mL !!

I did the ratio proportion, however I used the 200mg table. My question is, is there a formula for the 250mg?

Thanks :)

You need a pharmacist to answer that one for you. As far as I remember, amoxil always came in a standard strength, ie multiples of 125mg. I confess, I never came across the other doses mentioned. I could be wrong, but I think the final strength was not dependent on differing strengths of the active substance itself, but in the quantity of powder for reconstitution in the bottle, and the amount of water that was consequently added to it. This was according to instructions on the bottle or the package insert.

It's been about 25 years since I had to fiddle with reconstituting suspensions, so my memory is not to be relied on :D

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Ahh just saw it there and thought Id work on it for fun...just passed the math exam but hey ;)

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The Bottle of the generic drug Novamoxicillin contains 5000 mg amoxicillin as trihydrate. You are asked to add 60 ml water in two portions and shake well to make 100 ml of suspension. Each 1 ml conatains 50 mg of amoxicillin.

1ml = x x= 100 ml of suspension

50 5000 mg

I'm trying to figure out how much water to add to amoxicillin suspension. Unfortunately there is no information on the bottle or on the insert that tells you how to reconstitute it. It's supposed to make 120ml, 250mg per 5ml. I can't find any info anywhere about how much to add to make 120ml. If anyone knows or know where I can find out I'd really appreciate if you could tell me.

Thank you

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That was the first clue I gave you. Therefore, concerning the 120 ml of suspension, you need:

(250 mg : 5 ml) = (x mg:120ml)

x= 6000 mg.

Therefore, you need a powder of amoxicillin as trihydrate to make a suspension of 120 ml.

I think this will be helpful.

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