How to reconstitute amoxicillin?

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  1. This is a discussion on How to reconstitute amoxicillin? in Nursing and Patient Medications, part of General Nursing ... I'm trying to figure out how much water to add to amoxicillin suspension. Unfortunately there is no...

    by Feb 25, '11
    I'm trying to figure out how much water to add to amoxicillin suspension. Unfortunately there is no information on the bottle or on the insert that tells you how to reconstitute it. It's supposed to make 120ml, 250mg per 5ml. I can't find any info anywhere about how much to add to make 120ml. If anyone knows or know where I can find out I'd really appreciate if you could tell me.

    Thank you
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    by Tazike Feb 25, '11 3:52 pm
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  3. 12 Comments so far...

  4. Feb 25, '11 by
    Is there a pharmacy where you work that you can call and ask? If not, can you ask any of the other nurses where you work? I think they would be a better source of information than an Internet board.
    Altra and BabyLady like this.
  5. Feb 25, '11 by
    Check the pdr or other Drug manual.
  6. Feb 25, '11 by
    Here's a link that gives the info:

    http://www.google.co.za/url?sa=t&sou...upSvU5vUHdlztg
    Last edit by GHGoonette on Feb 25, '11
    Chin up and netglow like this.
  7. Feb 25, '11 by
    Are you sure you checked the bottle well? Ours comes with directions right on it, but the print is quite small and easy to miss.
    TaikoRN and sevensonnets like this.
  8. Guide
    Feb 25, '11 by
    Does your floor not have a IV med handbook. Our floor has one that gives all info on preparing and administering. Our amoxicillin comes with directions on the bottle too.
    sevensonnets likes this.
  9. Feb 25, '11 by
    Bottle Size Amount of Water Required for Reconstitution
    100 mL 74 mL
    150 mL 111 mL

    Each teaspoonful (5 mL) will contain 250 mg amoxicillin.

    I checked that link-I see it only mentions 200 and 400mg doses. The above is the correct reconstitution, but the OP mentions a 120ml bottle. Op, I would recommend that you first check what the quantity is supposed to be after reconstitution; if you are correct and it is supposed to be 120ml, the amount of water, judging by the above table, would be in the region of 89ml.
    MassED likes this.
  10. Feb 26, '11 by
    Hi, hope you dont mind, working on this for practice and got 90 mL !!

    I did the ratio proportion, however I used the 200mg table. My question is, is there a formula for the 250mg?
    Thanks
  11. Feb 26, '11 by
    Quote from studentpn73
    Hi, hope you dont mind, working on this for practice and got 90 mL !!

    I did the ratio proportion, however I used the 200mg table. My question is, is there a formula for the 250mg?
    Thanks
    You need a pharmacist to answer that one for you. As far as I remember, amoxil always came in a standard strength, ie multiples of 125mg. I confess, I never came across the other doses mentioned. I could be wrong, but I think the final strength was not dependent on differing strengths of the active substance itself, but in the quantity of powder for reconstitution in the bottle, and the amount of water that was consequently added to it. This was according to instructions on the bottle or the package insert.

    It's been about 25 years since I had to fiddle with reconstituting suspensions, so my memory is not to be relied on
  12. Feb 26, '11 by
    Ahh just saw it there and thought Id work on it for fun...just passed the math exam but hey