Yes, this kind of thing can lead to trouble ranging from deterioration of workplace relationships to serious consequences for employment. I have also learned from experience
that the general public does not often share in the humor that we do.
Having said that, there are a number of take-no-prisoners but gut-busting funny blogs out there written by folks of every medical stripe - nurses, physicians, pharmacists, EMS, etc. If you're contemplating this, give serious consideration to your pseudonym and what details you can alter to prevent identification.
And let us know your blog site.