Personally I love Queen's. It's a great hospital with a good amount of ancillary staff, support systems, they are a magnet facility. The staffing is pretty good. 4:1 med surg (maybe 5:1 in the day time depending if they are short). 3:1 for tele/chronic vent floor. 2-1:1 ICU. I think raising a family in Hawaii is a great, people are very welcoming.
The only thing I can think of is sometimes there is some reverse discrimination IMO that happens in Hawaii in general (if you are a mainlander, white, you might experience some discrimination). I'd say come with an open mind, don't have the "well I did it this way at blah blah blah" attitude and you'll be fine. Travelers I've spoken to have experienced it, and some have not. Not everyone is like this just a select few.
Housing can be very expensive, especially if you're going to be moving into town. I moved back from living in SF for 7 years (Hawaii is my home) so moving back felt a lot cheaper to me because SF was so expensive. The houses tend to be on the older side in town, so if you are looking to even rent something relatively brand new looking and cheaper, you're gonna have to rent out west (kapolei, makakilo, ewa, waipio). It is also way hotter weather-wise out west.
The other thing to consider is traffic. When I moved back from the mainland I was staying out west with my parents, I would have to leave at 5:30 to get into town by 6:30ish (and its only ~15 mile drive from my house to Queens). I moved into town and I walk to work now. Throw in an accident on the H-1 freeway and be prepared to feel like you're driving in a parking lot. Plus they're doing roadwork on a lot of roads now on the freeway and in town, so expect traffic at all times of the day
Traffic coming from the windward side (kaneohe, kailua) isnt nearly as bad, at least you have options when commuting (Pali Hwy, Likelike hwy).
Where are you from? Feel free to ask me anything, the Hawaii forums aren't as active as other forums so I'm trying to contribute as much as I can :-D