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Current is 250mL/500mg, 5mcg/kg/min, 242lb
If you need to double the drip rate by increasing both the volume and amount of drug in the bag (that just seems ridiculous, but I guess its just for practice in rearranging math equations) then use DA only. There probably isn't a formula specific to this.
16.5 X 2 = 33mL/h
mL/mg = 33mL/hr X hr/60min X min/110kg X kg/5mcg X 1000mcg/mg
= 33000mL/33000mg
This means you have to make a bag with drug that is a 1:1 ratio if you want to double the flow rate by changing the H and the V at that same time. To test this, lets do 1000mg of drug in 1000mL of solution
mL/hr = 1000mL/1000mg X mg/1000mcg X 5mcg/kg X 110kg/min X 60min/hr
= 33mL/hr
No matter bag you choose, as long as it is a 1:1 ration of drug to solution, you will get a flow rate that is double your first answer.
What is IV rate in ml/hr and give a H and V that will double this drip rate.
There must be a typo somewhere because if you wanted to double the drip rate you would multiply by 2 and get 33ml/hr. However that would also double the dose rate.
If the question is actually asking what would the concentration of Dobutamine be if you wanted the same dose rate (5mcg/kg/min) at double the drip rate. Then you would have to divide the concentration by 2. Instead of 500mg in 250ml it would be 250mg in 250ml.
Whatcha say mrsboots.
Thanks to everyone that answered. I copied the problem exact from a test we recently had so maybe my prof meant something else from what she asked or im over thinking it. I initially thought you could just change either the on hand quantity(H) or the volume(V) but prof said both would change so I wasnt sure then how to figure that out. An RN told me today that I would just change the 5mcg to 10mcg and not the 500mg or 250ml because that's "as it comes" so that confused me more.
Im still trying to understand what these kinds of problems are telling me so its hard to grasp the relationship between all the quantities and manipulate it for questions like this.
Ill ask a classmate what they did.
Thanks again for your replies
Have to think way back on this one...
Your method of calculating is what I learned in nursing school.
However, in practice it's more like this:
Concentration of drug x conversion to mcg/conversion to minutes
(500mg/250ccx1000mcg)/60=33.3 this is your "Constant"
(Dosexweight)/constant=cc/hr
Your example: (5mcgx110kg)/33.3=16.5 cc/hr
Not sure what else you are asking about H and V, but double the rate = double the dose (33 cc/hr = 10 mcg/kg/min)
Before smart pumps, we used to have to double check our pumps when we ran vasoactive drips but it's been a while so it took me a while to remember how. It works with weight based drips; non-weight based is similar.
tiffanyleto
9 Posts
Give dobutamine 500mg in 250ml D5W at5mcg/kg/min, wt = 242lbs.
What is IV rate in ml/hr and give a H and V that will double this drip rate.
I know how to find rate ml/hr and got 16.5ml/hr but I dont understand how to find out second part for H and V.
I found 16.5 by doing 110kgx5mcg/1kgx1min = 550mcg/min
Then used proportion to get 33,000mch/hr
And used DA 33,000mcg/1hrx250ml/500,000mcg = 16.5ml/hr
I have no idea how to find second part of problem
Thanks