It is my understanding that MRSA (and VRE I think) will often not even make a healthy person sick, but Hepatitis C is a serious threat to even a healthy individual with no effective vaccine available (and is easier to transmit than HIV). Yet "the wife" was discussing how she had a Hep C client today with open wounds, IV's and drains, but that wasn't an isolation client, and yet she had one with MRSA who was in isolation. What is the criteria and who makes the determination?