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Questions on PT, PTT, and INR



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  #1  
Old Jun 03, 2006, 07:05 PM
Registered User
Join Date: Dec 2005
Questions on PT, PTT, and INR

Hello,
I am hoping you can direct me or me with the explanation of PT, PTT, and INR. I know that all have to do with clotting and we look at PTT for Heparin and INR for Coumadin but I get confused with what is the difference between the 3 of them. I tried reading it in my lab manuel but that was as clear as mud!

I was hoping someone could point me in the right direction!!

Thank you,
Kate

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  #2  
Old Jun 03, 2006, 10:27 PM
Registered User
Join Date: Feb 2004
Re: Questions on PT, PTT, and INR

I will try...PT= measures the amount of time taken for clot formation after reagent tissue thromboplastin is added to the sample.
PTT= How well the the coagulation sequence is functioning by measuring the amount of time it takes for clot formation after partial thromboplastin is added.
INR= just a set standard rate
I don't know if that helped or not....its the best I can do

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  #3  
Old Jun 04, 2006, 02:58 AM
ZASHAGALKA's Avatar
ZASHAGALKA (Male)
Who's John Galt
Join Date: May 2005
Re: Questions on PT, PTT, and INR

Pt is an indicator for Coumadin, PTT for heparin, and INR is an international standardization of the relationship between the two values.

So, an INR of 1.0 would be a 'normal' relationship between the two values. An INR of 2.0 is normally the goal of anti-coagulant therapy.

As that INR slides above 2.0, the risks of bleeding go up greatly. IF the doc is checking to see that someone has been off Coumadin long enough for tx (surgery?), they are checking to see that both PT and the relationship, the INR, are returning to normal values.

Here's a way to remember the values w/ what they check:

PTT Heparin: 10 letters
PT Coumadin: 10 letters

If you line them up right, the number of letters match.

~faith,
Timothy.

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  #4  
Old Jun 04, 2006, 03:41 AM
Angie O'Plasty, RN's Avatar
Joule of an RN
Join Date: Aug 2004
Re: Questions on PT, PTT, and INR

I like that memnonic, Tim!

My way to remember it was by counting the T's.

PT/INR stands for ProThrombin--one T.

APTT stands for Activated Partial ThromboplasTin time--2 T's. I also noticed that APTT is for heparin, which usually has to be checked "Twice" as often.

(Don't ask me why I could remember Activated Partial Thromboplastin Time just fine and had trouble remembering which test went with which med, though. )

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  #5  
Old Jun 04, 2006, 05:57 AM
VickyRN's Avatar
Nursing Champion
Join Date: Mar 2001
Re: Questions on PT, PTT, and INR

Great information in this thread also

http://allnurses.com/forums/f205/can...hlight=heparin

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  #6  
Old Jun 04, 2006, 07:09 AM
Registered User
Join Date: Dec 2005
Re: Questions on PT, PTT, and INR

Thank you everyone for your responses! I understand it a lot better.

Thanks again!
Kate

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  #7  
Old Jun 04, 2006, 09:03 AM
Registered User
Join Date: Feb 2004
Re: Questions on PT, PTT, and INR

OK so I gotta add the way I keep them straight! PTT= Heparin... connect the two T's looks like an H. So the PT has to be coumadin.

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