Definitely get the guide printed and bound and read through it cover-to-cover first thing. Don't try to memorize it yet, just read it to get familiar with it. It helped me to keep Unit V in a separate binder and tab it off further (dividers between Section A, B, C etc.).
I broke the CPNE down in to four areas:
Labs + PIE (Planning, Interventions, Evaluation)
I set up a lab immediately and went through all my lab stations every day. You will fumble through them at first. Don't get discouraged. You will get better.
I knew that planning was my weakest area and intervention was my strongest, so I started with Planning and focused on it, all the while practicing my labs and studying the study guide. I tried to read the guide at least once a month every month.
I also highly recommend keeping a notebook and jotting down questions. You can submit your questions through the message center. I would read the study guide at least twice before starting to submit questions though, because most of your questions will be answered in the study guide.
Youtube is also a great resource for brushing up on basic nursing skills; just keep your critical elements in mind while watching the videos.
I also found the flash cards that the school sells to be invaluable! Just not the audio ones, lol.
Someone here suggested a small dry erase board to practice writing your grids and they were spot on....
But first, read the study guide