As an NP in California, where recreational marijuana use is now legal, I am concerned about possible marijuana-medication interactions. There is a lot of information on ETOH - medication interactions, but I haven't seen specific information pertaining to marijuana. Today, I came across an article suggesting marijuana can increase blood pressure, sometimes fatally (see below), so that suggests HTN patients should not smoke pot. Would greatly appreciate information and/or experiences around this.
Marijuana use holds three-fold blood pressure death risk: study | Reuters
Probably the best presentation I've seen on it is: https://doh.dc.gov/sites/default/fil...ractions_0.pdf
- District of Columbia Department of health on medical cannabis averse effects and drug interactions
Cytochrome P45 enzymes involved in the metabolism of tetrahydrocannabinols and cannabinol by human hepatic microsomes. - PubMed - NCBI
- Article citation on THC and CBN CYP450 Interactions that's also helpful
I'd also check out Scientific Publications
as they have a whole center for medicinal cannabis research.
Last edit by JustKeepDriving on Aug 10
: Reason: Additional Info