Whatever happened to Anzemet?

[NurseCard, ADN]

Was just reading a thread on here about IV vs PO meds for nausea,

and it took me back to my salad days as a nurse, lol. 13 years ago

when I was working on a primarily post surgical Med Surge floor...

our nausea medications of choice were Phenergan and Anzemet,

both IV.

Nowadays we mostly give Zofran. Back when I started, again,

13 years ago :), Zofran was mostly given on the OB/L&D unit.

These days, I know that Phenergan is rarely given IV anymore,

and we don't even give it PO very often. But what happened to

Anzemet? Seems like I gave Anzemet more than anything else.

Wonder why it isn't given much anymore.

[wtbcrna, MSN, DNP, CRNA]

It has the same mechanism of action as Zofran and hasn't shown to be anymore effective than zofran. Ondansetron versus dolasetron: a comparison study in the prevention of postoperative nausea and vomiting in patients undergoing gynecological proce... - PubMed - NCBI

[offlabel]

Seems like I gave Anzemet more than anything else.

Wonder why it isn't given much anymore.

I stopped giving it because it came in those dumb .5 ml amps that were a hassle to work with. There was as much medicine in the pop off part of the amp as there was I the vial itself. An unnecessary struggle to get it to fall into the vile. When Zofran came out with the 2 ml flip top vials, I switched.