suboxone and sublingual narcan
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Suboxone is taken sl. The idea is that the narcan will not be effective if taken sl, alowing the bupenorhine into the system.. If crushed and injected, the narcan will bind with the receptors instead, limiting abuse potential.
The naloxone component in SUBOXONE is included to help discourage diversion and misuse. Naloxone has very limited bioavailability when administered sublingually, as intended. However, if SUBOXONE is crushed and injected, the naloxone will precipitate opioid withdrawal. In the absence of an opioid, the antagonist has no effect.
http://www.suboxone.com/hcp/suboxone/
So- here is my question:
Narcan can be given sublingually.
http://groups.msn.com/paramedicemtgathering/medicaltopics.msnw?action=get_message&mview=0&ID_Message=6687&LastModified=4675677423197787354
I have heard other references to sublingual administration of narcan, but can find nothing documented anywhere.
SO- Is Narcan effective SL?
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