Published
out of curiosity...
what meds do your docs like to use for RSI. anybody using ketamine, read that it can be useful in hypotensive pt.s and especially with status asthmaticus.
I agree that lidocaine is a great drug, but may not always be the best choice with cerebral injury.
Lidocaine preferentially blocks inhibitory pathways centrally and may invoke excitatory phenomena (i.e. seizures) at clinical doses thus increasing CRMO2 which could accentuate apoptosis and cerebral edema. There are several articles from the neuroanesthesia department at Barnes-Jewish in St. Louis that describe this event very well.
Mike
I agree that lidocaine is a great drug, but may not always be the best choice with cerebral injury.Lidocaine preferentially blocks inhibitory pathways centrally and may invoke excitatory phenomena (i.e. seizures) at clinical doses thus increasing CRMO2 which could accentuate apoptosis and cerebral edema. There are several articles from the neuroanesthesia department at Barnes-Jewish in St. Louis that describe this event very well.
Mike
Therapeutic Drug Monitoring: Volume 22(3) June 2000 pp 320-322
Lidocaine and Seizures
DeToledo, John C.
Department of Neurogy, University of Miami, Miami, Florida, USA
jayne109, RN
141 Posts
we use etomidate and sux on just about everybody as well. Once intubated, we give norcuron, versed and occasionally (for trauma pts especially)fentanyl.
just my 2cents