Remdesivir Does Not Reduce COVID-19 Mortality per WHO study

[NRSKarenRN, BSN, RN]

WHO sponsored study of over 11,000 COVID-19  positive hospitalized patients is awaiting peer review. Karen

Medscape News October 16, 2020

Remdesivir Does Not Reduce COVID-19 Mortality, Study Says

Quote

A large study sponsored by the World Health Organization found that remdesivir doesn't help hospitalized patients with COVID-19 survive and doesn't even shorten the recovery time of those who do survive.

These findings contradict smaller studies which found remdesivir, an antiviral drug, helped hospitalized coronavirus patients recover faster than patients who received a placebo. Those earlier studies led the FDA to grant emergency use authorization for the drug, which has been given to thousands of COVID patients in the United States, including President Donald Trump.

The WHO-sponsored study was conducted from March 22 to Oct. 4 and involved 11,330 patients from 405 hospitals in 30 countries. Patients were given remdesivir and three other drugs singly or in combination.

"These remdesivir, hydroxychloroquine, lopinavir and interferon regimens appeared to have little or no effect on hospitalized COVID-19, as indicated by overall mortality, initiation of ventilation and duration of hospital stay," the study concluded....

 

10/15/2020  Med RX IV preprint of study:

Repurposed antiviral drugs for COVID-19; interim WHO SOLIDARITY trial results

https://www.medrxiv.org/content/10.1101/2020.10.15.20209817v1