If the PICC is designed with clamps, it probably lacks an integral PASV (pressure activated safety valve) and would need to be clamped while changing the injection caps. If the PICC does not have...
Small syringes should not be used for PICC flushing because they generate too much pressure. A 10cc syringe is used for the saline flush. If there is a heparin flush, it follows the saline and is...