Pick up the Chocolate?

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Article isn't only about the science behind which admittedly is my passion. It's about weight loss and staying Skinny. I'm American but grew up in London and have lots of family still there. Whenever I go over for holidays, it's sausages, bacon, bread, roast dinners, puddings, custard and the best chocolate in the world. I pack the pounds on. When I get home, I have this setup in my spare room.

A treadmill with a flat screen on the wall. DVR with a Bluetooth headset. I watch my shows, use the treadmill and before you can say, Bob's your uncle, an hour has gone by. Four days a week and I stay at 115 lbs. I eat a lot of chocolates and without my setup I'd be heavy. Keeps me fit because I'm a fiesty, spoilt brat. Really spoilt by my Dad.

Read the article as well. Good science.

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Specializes in ICU, LTACH, Internal Medicine.

Since what time "The Guardian" became a peer-reviewed periodical?

It all sounds cool, only one problem is that there is no such thing as "retired cell" in human body. Maybe with exclusion of female oocytes (which DO become "retired" after menopause). The rest are there for some purpose, all of them. A human being cannot live even without that 0.1 mm of already dead cells of stratum corneum covering his body and about 2 g at least of them being lost every day. Losing ALL these cells and their supported layer at once without injuring the derm itself is named "second degree burn, 100% TBSA" and leads to quick death without modern life support.

There are tons and tons of articles about ability of certain chemicals and substances, like melatonin, DIM, high doses of ascorbic acid and many more to somehow "purge" our body from "unwanted" oxygen radicals, products of their actions, cell debris, "toxins" (whatever the heck they might be), etc. The place below has tons of scientific info for anyone interested to dig into and enjoy, just ignore ads:

Independent Analysis on Supplements & Nutrition | Examine.com

As it appears to be so far, while approximately 1/3 cases of cancer can be potentially prevented by modifying environment, diet and all that, the rest can be neither predicted not prevented due to the fact that mutagenic processes of nucleic acids are very well described within mathematical probability models. In other words, if one lives long enough, at one time some of the cells WILL become cancerous and everything that could be done about it is to find and kill that cell line before it becomes full-blown malignancy. Cancer, Alzheimer, OA and many other modern diseases are just what they are: price for living much longer than we humans are actually designed to. Biologically, our lives make sense till we can multiply. Once we stop producing offsprings, we should die in order to free resources for the next generation.

While it makes sense to reasonably limit modern indulgencies and known bad habits in order to prevent what we can prevent, I am now quietly salivating in anticipation of spending a few days in London, England this summer and enjoying REAL. ENGLISH. BREAKFAST. every single one of them. With bacon, three kinds of ham, eggs, kedgeree, kippers and fried bread, please. And then lunch, five-o'-clock tea (REAL. ONE. with seedcake and scones, with REAL butter on them) and dinner. All "retired cells" be ****ed. Life is too short anyway.

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Katie, I think you may have forgotten beans and grilled tomatoes and lashings of tea. Also try our kebabs and Chinese. Curry houses everywhere.

I think science re models etc has its place but the mice says different. Also, studies re environment changes, diet and exercise shows that differences can be achieved. And that's on a human level. Mice do not have that capability so something must have occurred to reverse those aging effects. Recent French procedures re sickle cell etc? When you consider that 90% of proteins are still uncharted, I read somewhere, or their exact uses and interactions. Telomeres and cell death. Quite a few other species with longevity success? I'd say we still have a long way to go.

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