Ampicillin for GBS patient with imminent delivery???

Specialties Ob/Gyn

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Hey fellow nurses! This is my first post here. I'm excited to be part of this community.

I'm wanting feedback about a case I had tonight. My patient was a primip, came in with SROM, and her VE was 5cms. Another nurse had admitted her, and I received her as a patient at 0315, just as she was getting her IV. I collected the chart and set out to take care of her. I saw no prenatals, so I got them out of the drawer, at which time I saw she was GBS +. I called the dr. to get orders for ampicillin. It was about 0335. About 5 minutes later, she called me and told me she wanted her epidural. I called anesthesia and then went to go get my ampicillin. Not 3 mins later, she called me again to say she had an urge to push. I hadn't had time to mix my ampicillin yet. I checked and she was complete, and +2 station. We cancelled the epidural and told the doctor to come in. I pushed with her for 1/2 hour and the doctor arrived. Since I knew delivery was immenent (she was pushing wonderfully) I didn't give the ampicillin. When the doctor arrived, at 0420, I told him this, and he was upset and told me to give it anyway. So, whatever... I did. She delivered at 0435.

I find this so wasteful. The research shows (so I thought) that you need AT LEAST 2 hours before delivery for the ampicillin to benefit the baby, and more likely, 4 hours.

Is this what you guys know to be true, too? What are you thoughts? What would you have done?

Thanks in advance for your thoughts!

Specializes in Perinatal, Education.
I think when we support each other, we all benefit. I really learned something from this, and in the future, it's going to benefit my patients as well as myself... I'll always push Amp no matter how soon that baby is coming out!

On a related note... Do you guys ever fudge and give the 2nd dose early (say at a 3 hours interval) when it seems like baby is going to come before the 4 hours are up? I've occasionally given a 2nd dose at like, 3 1/4 hours. Anyone else?

Incidentally, I've been a L&D nurse for 7 years, too! But, with 2 years off in the middle to have my twins : )

Thanks again!

Don't you have a half hour either way?? so 3 1/2 hours isn't really fudging. I've been known to stretch the envelope a bit. Better than no coverage or too late to help.

Hey fellow nurses! This is my first post here. I'm excited to be part of this community.

I'm wanting feedback about a case I had tonight. My patient was a primip, came in with SROM, and her VE was 5cms. Another nurse had admitted her, and I received her as a patient at 0315, just as she was getting her IV. I collected the chart and set out to take care of her. I saw no prenatals, so I got them out of the drawer, at which time I saw she was GBS +. I called the dr. to get orders for ampicillin. It was about 0335. About 5 minutes later, she called me and told me she wanted her epidural. I called anesthesia and then went to go get my ampicillin. Not 3 mins later, she called me again to say she had an urge to push. I hadn't had time to mix my ampicillin yet. I checked and she was complete, and +2 station. We cancelled the epidural and told the doctor to come in. I pushed with her for 1/2 hour and the doctor arrived. Since I knew delivery was immenent (she was pushing wonderfully) I didn't give the ampicillin. When the doctor arrived, at 0420, I told him this, and he was upset and told me to give it anyway. So, whatever... I did. She delivered at 0435.

I find this so wasteful. The research shows (so I thought) that you need AT LEAST 2 hours before delivery for the ampicillin to benefit the baby, and more likely, 4 hours.

Is this what you guys know to be true, too? What are you thoughts? What would you have done?

Thanks in advance for your thoughts!

You are correct. If it was not 4 hours your baby should get a cbc/diff and cultures.

Specializes in Specializes in L/D, newborn, GYN, LTC, Dialysis.

Yes, I have given Amp 30 minutes early at times when labor appears to be moving along fast.

Specializes in Nurse Manager, Labor and Delivery.

I was at a seminar not to long ago and a perinatologist was talking about the use of Amp instead of PCN. PCN is THE drug of choice in treatment of GBS...according to the CDC and the American Academy of Pediatrics. Seems that you should only use AMP is PCN is not available. We changed our policy based on this evidence based practice. Apparently you can be found negligent if you are using AMP instead of PCN and PCN is available. Just thought I would pass that along.

There is also contention now between Peds and OB about treating or not treating GBS in term patients...I haven't read the study yet...but one doc is saying not to treat. It surely heats up the Peds folks...lol...

We try to get in the dose if possible...if not we keep the baby for 48 hours. Depending on the kid, we get cultures and CBC, it really depends on the doc that is attending.

It is so great to see what other folks are doing. I love this site...

Specializes in Specializes in L/D, newborn, GYN, LTC, Dialysis.

do you have a way to point me to the literature on this??? I will search, but if you have it handy, I would love to show it to our OB's cause NOT ONE OF THEM wants to change to PCN. THANK YOU SO MUCH!

Specializes in Nurse Manager, Labor and Delivery.

Yes I do..but I am going to have to find it. I met with GREAT resistance when I first broached the subject. Then our OB chief went to a conference and heard the same thing..and POOOF...it changed...go figure.

I know you can find recommendations on the AAP site..and the CDC site...but I have to find the reference from the guy who gave the lecture.

What about this...let's give everyone AMP prophylactically just in case "they might be" GBS pos??? You may think I'm kidding, but this is the way we really do it. I guess the bright side is that none of our babies get sick. :uhoh21:

Specializes in Specializes in L/D, newborn, GYN, LTC, Dialysis.
What about this...let's give everyone AMP prophylactically just in case "they might be" GBS pos??? You may think I'm kidding, but this is the way we really do it. I guess the bright side is that none of our babies get sick. :uhoh21:

Using antibiotics so cavalierly is what creates super-strains, remember. We must use them judiciously, not at-will.

Specializes in Specializes in L/D, newborn, GYN, LTC, Dialysis.
Yes I do..but I am going to have to find it. I met with GREAT resistance when I first broached the subject. Then our OB chief went to a conference and heard the same thing..and POOOF...it changed...go figure.

I know you can find recommendations on the AAP site..and the CDC site...but I have to find the reference from the guy who gave the lecture.

I will go look at those sites. Thank you. At one place I worked, we used PCN for GBS pos moms---- but where I work now, it's AMP or Clindamycin--- or Erythromycin (one doctor tests WHICH strain, and if it's cillin resistant, uses Eryth.) Thank you for this info. I am always wanting to learn something.

Using antibiotics so cavalierly is what creates super-strains, remember. We must use them judiciously, not at-will.

I completely agree. How do you educate the "almighty" doctor though? Most take offense at the very suggestion of something. Their rationale is that you can convert from being GBS negative to positive during the last few weeks of pregnancy. "It's not an expense we are not going to pass along to our patients because the practice is completely inaccurate." :uhoh3: I would like to see some literature on this but have not been able to find anything.

Specializes in Perinatal, Education.
I completely agree. How do you educate the "almighty" doctor though? Most take offense at the very suggestion of something. Their rationale is that you can convert from being GBS negative to positive during the last few weeks of pregnancy. "It's not an expense we are not going to pass along to our patients because the practice is completely inaccurate." :uhoh3: I would like to see some literature on this but have not been able to find anything.

Because they can become positive during the last few weeks of pregnancy, our docs don't swab them until about the 36th or 37th week. Because of this, we do sometimes get patients who don't have results yet and we either do a rapid test swab or treat them as if positive depending on the situation. We only use PCN unless it isn't available. Only problem is that it is sometimes very painful going in.

Specializes in Specializes in L/D, newborn, GYN, LTC, Dialysis.

Our docs swab after 37 weeks.

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