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Just wondering how much narcotic, specifically fent. you give for a typical Lap Chole. I have experienced 3 cases this week were I had to give a very small dose of naloxone to get the patient back breathing. (ET Sevo 0.1, fully reversed, ETCO2 45- 50 and still not breathing.) I typically have the agent off at the time the trocars are removed from the abdomen.
And your ephedrine/neo/vasopressor of choice!
Well, not necessary! If you keep opiate levels low, you´ll use more gas to keep intraop stress levels down. If you in that situation give fentanyl you´ll surely have a blood pressure drop. But the drop in BT isnt a direct farmacological effect of fentanyl, its the fentanyl that removes the "pain" that kept the patients BT up earlier.
If you start with a stiff dose (the dosages that Snakebite propose) with opiate at induction time, and afterwards just add gas - youll find yourself using much less agent. And you also get a very circulatory stable patient too. Circulary stable, but hard to get to breathe sufficiently afterwards in a reliable way.
The first time I emtied a full 20 ml syringe of fentanyl into a patient, I admit it felt adventurous.. I was used to tosages of 5-10 ml per case. (0.05mg/ml)
High dosages of opiates has distict advantages, especially with circulatory challenged patients. It has its distinct drawbacks too - respiratory depression.
/Anders, Nurse Anesthesist, Sweden
snakebitten
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