IV drug (Chemistry) question

[ghaleon128]

Hopefully someone can help me out on this. I have a test question that I'm kinda stumped on. It's a take home test so we can use all resources to answer the question. The t/f question is, "Drugs that are insoluble amines may be delivered intravenously if they have been reacted with a strong acid, such as HCl, because the ionic salt that forms is water soluble."

I know certain drugs are made into a salt so that the drug becomes water soluble, but am I missing something in the question? It seems too easy, that's why I ask. Any help would be much appreciated!

[leslie :-D]

Hopefully someone can help me out on this. I have a test question that I'm kinda stumped on. It's a take home test so we can use all resources to answer the question. The t/f question is, "Drugs that are insoluble amines may be delivered intravenously if they have been reacted with a strong acid, such as HCl, because the ionic salt that forms is water soluble."

I know certain drugs are made into a salt so that the drug becomes water soluble, but am I missing something in the question? It seems too easy, that's why I ask. Any help would be much appreciated!

true.

hope the following link works.

scroll down to "wikipedia", then read under "uses".

http://www.answers.com/topic/hydrochloride?cat=health

leslie

[Beggar♂]

"Drugs that are insoluble amines may be delivered intravenously if they have been reacted with a strong acid, such as HCl, because the ionic salt that forms is water soluble."

Warning: I am NOT a nurse so I could be way off here but here's a chemist's take on it...

Amines have the structure R-NH2. If the R group is large, uncharged, and/or nonpolar, it may be insoluble. Recall that amines are weak bases. In the presence of a strong acid, the -NH2 group will be protonated and you'll end up with R-NH3(+)Cl(-). The charged amine compound are now soluble.

Presuming this is acceptable intravenous practice, the compound could be delivered to the patient.