How long does Neurontin take to work?


Anyone? I started this today for pain control, etc. Thanks!


133 Posts

Specializes in med/surg. Has 12 years experience.

According to Davis' Drug guide onset is rapid, peak is 2-4 hours and duration is 8 hours. Since it is an adjunct for neuro pain mgmt you may need to take it around the clock (ATC) for a while to get effective pain control. Make sure you continue to take your other analgesics with the neurontin, and let your prescriber know how effective it is for you.

May your pain become a distant memory. :balloons:


464 Posts

I have been taking Neurontin since January for pain associated with bulging lumbar discs. I gradually ramped up to 300 mg 3x a day and noticed defiinite side effects of confusion and inability to concentrate. My doctor left me at that dosage for a month, with no improvement, so he started to wean me from it. The first day I dropped a pill, I noticed an significant increase in the leg pain, numbness and tingling. What I thought wasn't working for my pain most certainly was. I bit the bullet and had him ramp up the dose to 600 mg 3 x day. The side effects disappeared with the larger dose, and I have little to no leg pain.

Some people take much larger doses than I do. It was hard to tell how it was working with the other meds I was taking as well as the progress of physical therapy. It did, however, work. I do have narcotics of breakthrough pain but do not need them much. HTH

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