is gliclazide listed in your drug book? please help w/info!

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I need some info on gliclazide (sold as diamicron in canada). Can't find it in prentice hall 2009 + davis 2008 (i think) drug guides... This drug is a 2nd gen. sulfonylurea antidiabetic agent. I need some information on important nursing interventions to include in a nursing process outline for administering this med.

I have a NIDDM pt. (w/ chronic renal failure, HTN, CHF) taking 80mg PO bid... according to drugs.com this usual dose is 80mg QD or 160-320mg in two divided doses with meals for tx of type II diabetes

Will the nursing considerations for this medications differ greatly from other meds in its class? My guess is 'not', but I'd rather not be guessing here. Please help! Thanks in advance :)

Specializes in Maternal - Child Health.

I think you man glipizide.

Maybe... glipizide is listed in prentice hall with the trade names "glucotrol" and "glucotrol XL". The availability is in 5mg and 10 mg tablets or SR tablets... in the MAR I'm using for this pt, it states "one tablet" under the listing for gliclazide, 80mg...

*sigh*

This is the link I was looking at: http://www.drugs.com/cons/gliclazide.html

I'm sure that the drug are really, really similar, which is why I'm sure the ns. considerations for any in that class are also really, really similar...

Maybe... glipizide is listed in prentice hall with the trade names "glucotrol" and "glucotrol XL". The availability is in 5mg and 10 mg tablets or SR tablets... in the MAR I'm using for this pt, it states "one tablet" under the listing for gliclazide, 80mg...

*sigh*

This is the link I was looking at: http://www.drugs.com/cons/gliclazide.html

I'm sure that the drug are really, really similar, which is why I'm sure the ns. considerations for any in that class are also really, really similar...

are you in canada, because it is listed as not commercially available in the states......

yes I'm in canada... I know the drug isn't available in the states. I suppose this is why my drug guides don't list it...

Specializes in med/surg, telemetry, IV therapy, mgmt.

In the U.S. this is glimepiride (brand name Amaryl) and glipizide (grand name Glucotrol), a 2nd generation antidiabetic sulfonylurea. Here are the nursing considerations for it from my copy of 2007 Mosby's Nursing Drug Reference page 509:

Assess:

  • Blood, A1C levels during treatment to determine diabetes control

  • CBC baseline and throughout treatment

  • Hypo/hyperglycemic reaction that can occur soon after meals; for severe hypoglycemia give D50W then IV dextrose solution

Administer:

  • Do not break, crush or chew ext rel tabs

  • Drug 30 min before meals; if pt is NPO may need to hold dose to prevent hypoglycemia

  • May crush tabs and mix with fluids, if unable to swallow whole

Perform/provide:

  • Storage in tight, light-resistant container at room temperature

Evaluate:

  • Therapeutic response: decrease in polyuria, polydipsia, polyphagia, clear sensorium, absence of dizziness, stable gait

Teach patient/family:

  • Not to drink alcohol; explain disulfiram reaction (nausea, headache, cramps, flushing, hypoglycemia)

  • To check for symptoms of cholestatic jaundice: dark urine, pruritis, yellow sclera; prescriber should be notified

  • The symptoms of hypo/hyperglycemia, what to do about each; to have glucagon emergency kit available, carry sugar packets

  • That drug must be continued on daily basis; explain consequences of discontinuing drug abruptly

  • To take drug in morning to prevent hypoglycemic reactions at night

  • To use sunscreen or stay out of sun to prevent photosensitivity

  • To avoid OTC medications unless ordered by prescriber

  • That diabetes is a lifelong illness; drug will not cure disease

  • That all food in diet plan must be eaten to prevent hypoglycemia

  • To carry emergency ID with prescriber and medications

  • To test using blood glucose meter while on this drug

  • To continue weight control, dietary restrictions, exercise, hygiene

  • Ext rel tab may appear in stool

Treatment of overdose:

Glucose 25 g IV via dextrose 50% solution 50 ml or 1 mg glucagon

Thank you so much!

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