My experience (diploma, BSN, MSN) is that nursing classes are pretty "intimate". They may teach all 147 of you some things simultaneously, but by and far, they will break you down into some more manageable number. You cannot simultaneously have 147 people paired up learning to give bed baths or change an occupied bed all in one room. I don't think many schools have that kind of space. So you will find yourself in smaller groups. I came from a small basic diploma program and, for example, during our Maternal Child Health rotation, we didn't ALL go to L & D together. some of us were on peds, others on pp, others in nursery and others in L & D.
In my diploma program, likes did a lot of (but not exclusively) pairing with likes: young married nurses found each other, we dorm dwellers hung together, more mature students found each other. In my BSN, BSN completers hung together, not as fiercely as we did in our basic program, but we were more alike (and for the most part did not "mix" curriculums with the generics). In the MSN program, they did not admit and graduate us as a class since they allowed part time study in my MSN program, but you always managed to migrate from class to class and find SOMEONE you knew while you all herded to the pop machine at break AND nursing curricula is to be depended upon for putting you into groups to work on a project so that you get to know each other.
In my first sentence, I talked about intimacy. When you do labs where you undress for physical assessment, give shots to each other (in my time) and just spend so much darn time together, you do meet people you come to know and bond with.
I went to a very small junior college in the middle of a KS wheat field, then I went to a diploma program, where we probably had 28 to 32 grads, tops, and then I went to a medium sized college for my degrees, with huge lecture halls and large buildings. In truth, the big college is like living in the big city. I knew the health sciences building well, the LIBRARY well, the student union (where they sold chocolate brownies on the inconsolable days) and was forced to venture into other buildings occasionally. You don't have to do it all at once. It is manageable. In high school you think that being in the wrong classroom will cause you to melt with shame. By college EVERYONE has had the experience of being lost and so you plan ahead (go find your classrooms on registration day, go scope out the hospital before you have to be there for clinicals & usually that's part of your orientation to the hospital, at least early on) and try to leave yourself extra time for brain farts.
In order to go to college, I left the community I trained and moved to the "big" city, tertiary care hospital. Like most tertiary care centers, the building "grew up" in generations and there were plenty of places that you couldn't get to from one elevator. I worked the ED and unashamedly asked directions before I would take patients to the floor and carried a map in my pocket for many a month. But I survived only slightly scarred
Bottom line, is just take it easy. You will find some folks new to the campus like you and some folks who know the campus. Allow yourself extra time (parking and driving in the "big city" AND finding your target destination) and know you arent' alone.
I do admire you for going to the bigger setting. In the final analysis, you won't regret it.