1. Saw an ad on TV the other day for Flexium and wondered what that was, looked it up and found it is SAM-e, looked that up and found the following:

    SAMe is short for S-adenosylmethionine, a substance that occurs naturally in the body. It's a combination of two essential amino acids and plays a role in as many as 35 to 40 biochemical reactions throughout the body. Usually the body can make all the SAMe it needs, but patients with depression and other conditions have been found to have lower levels of the compound.

    Anybody have any experience with this product for either arthritis or for depression? I was thinking it might be beneficial for my mother who has joint pain and also (I think) some issues with depression that she would never admit to.
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  3. by   ShandyLynnRN
    hmm, never heard of it... I'll have to check into that. I wonder if it can be taken in addition to antidepressants.
  4. by   sunnygirl272
    appears it can and should be taken with antidepressants...check out GNC....

    about SAMe

    drug intereactions

    shouldn't be used in parkinson's or bipolars...

    think i'm gonna get me some....
    Last edit by sunnygirl272 on Mar 2, '03
  5. by   renerian
    Yes I learned about that in my BS program. In other countries they take SamE as an antidepressent with some good some not so good results.

  6. by   Katnip
    I took it for depression. It actually helped me a lot. Better than some of the prescriptions I'd taken. Unfortunately, at the time it was very expensive-almost $70 a month. Not sure if the price came down. I used the Nature Made brand because I'd read in a consumer magazine it was the only one that had a consistent dosage level.
  7. by   renerian
    Consistent dosing is one of the problems with many of the over the counter preparations. Good point.

  8. by   K O'Malley
    I took Sam-E for help with joint problems and had a bizarre reaction of severe tinnitus, photophobia, and nightmares. I'm not on anti-depressants so I don't know what happened. I did have wine with dinner but don't know if that is what triggered the reaction or not.