GO FOR IT!
I came back after 11 years. Took a 3 month nurse refresher through a community college in 1995. It was the best thing I could have done!
My classmates (who had all been out longer than I had) and I were treated as adult returning learners, and respected for our knowledge and previous experience. We reviewed the "basics", and were brought up to date on cardiology, chemo, how to review new meds, IV techniques, physical assessment, and the current roles of nurses and how to market ourselves in the "new world". Clinicals really boosted my confidence, too.
Got a hospital job soon after finishing the program, med surg floor, and love it still.
My med knowledge is still not so great in some areas, and I OFTEN have my nose in the drug handbook
at med pass time. You get pretty knowledgeable about the meds you use all the time, but it feel like there are new meds out every week!
I am going to check out Lansing C. C.'s on-line Pharmacology course this spring.
Best of luck to you! Us seasoned (old?) nurses still have a lot to offer!