DOes anyone get the Medscape daily reports?
I found this today and it's intriguing.
April 21, 2003-Baclofen acutely reduces symptoms and episodes of gastroesophageal reflux disease (GERD) and raises gastric pH, according to the results of a study published in the April issue of Gut. Symptomatic improvement continued for the four weeks of the study, which suggests that this may be a viable alternative treatment for GERD. Baclofen is approved by the Food and Drug Administration, but not for this indication.
"In normal human subjects and in patients with [GERD], recent studies have shown that baclofen reduces the rate of transient lower oesophageal sphincter relaxations, the rate of gastro-oesophageal acid reflux episodes, and increases basal lower oesophageal sphincter pressure," write A. F. Ciccaglione and L. Marzio from the University G d' Annunzio, in Chieti-Pescara, Italy. "Baclofen therefore has been proposed as potentially useful in the treatment of [GERD]."