Can you expound a little more on what you are looking for with these two hormones? Each one varies in levels according to a woman's age group, whether she is pregnant or not, middle of the cylcle hormone fluctuations, menopausal changes cause a great deal of fluctuations in those two hormones, and post-menopausal women may or may not need a healthy balance of hormone replacements with those two hormones. So...is there a specific group of women you are targeting in relation to the side effects?
As for myself...at age 50...I still get the once a month moodswings mid-month when my progesterone levels are skyrocketing off the wall. My breasts are tender and sore.....can't stand to have them touched by clothing, hubby, or me for that matter. And, my moods are all over the place. Those are my progesterone side-effects.
With estrogen......I am not experiencing an estrogen loss as yet, but I hear that when a woman is in active menopause, she begins to experience vaginal dryness.....many lubricants are on the market for that, so no big deal there. That's one side effect.
Other side effects of estrogen: lack of estrogen in the woman effects the heart, the bones, the sex drive, etc.
I hope these things are what you are wanting. If not, feel free to let me know, and I'll try to answer your question more definitively. :kiss