Epinephrine for Bradycardia in PALS but not ACLS

Nurses General Nursing

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Hi,

I was wondering if anyone knows (the reasoning behind) WHY epinephrine is given for bradycardia in PALS (to pediatric patients) but not in ACLS (for adults)?

For adults, the first drug given in ACLS is atropine...

Thank you

I really do not know the answer to this, however, I can take a stab at it--perhaps because in pediatrics, the main reason one goes into cardiac arrest has to do with respiratory distress (unless there is unknown cardiac issues). Additionally, peds have a faster and more profound reaction to epi than adults--and atropine given to children can be risky.

Medscape: Medscape Access

Specializes in Critical Care, ED, Cath lab, CTPAC,Trauma.

An immature nervous system. Also children...babies lack the ability to increase the strength of the contraction to increase cardiac output...they only increase heart rate. So.....to increase perfusion and cardiac output thereby increasing end organ perfusion Epi is used.

In the face of decreased perfusion, epinephrine is used to produce alpha-adrenergic

vasoconstriction which increases systemic vascular resistance. This results in

increased aortic diastolic pressure, improving coronary and cerebral perfusion

http://www.medicine.virginia.edu/clinical/departments/pediatrics/education/pharm-news/2006-2010/201007.pdf

Hi, thanks for the responses. Very interesting. Your responses have been helpful. I also read that stressed neonates quickly deplete their own stores of catacholamines so epinephrine is given first to elevate the heart rate.

Specializes in NICU, PICU, PACU.

We pretty much only use Epi. On rare occasion, usually with an older kid do we use atropine. You can also use Epi down the OET which comes in handy in the DR when there is no access!

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